Endometrial Mosaic Creation Via Visual Motion Tracking

描述（由申请人提供）： 宫腔镜成像是评价子宫的重要诊断工具。然而，操作内窥镜以连续地可视化整个子宫内膜腔在技术上具有挑战性，并且受到陡峭的学习曲线的影响。这促使我们公司设计了子宫内膜镜，它使用全方位的尖端，矫正软件和一个自动化的方式产生子宫内膜的单一视觉地图。 我们现在建议研究使用视觉运动跟踪来创建子宫内膜腔的马赛克。这项技术将带来三大优势。首先，我们将能够补偿透镜的简单线性位移之外的运动（例如旋转、变形和缩放）。其次，由于软件可以跟踪示波器的自由移动，因此无需笨重的安装和安装。第三，子宫角的成像将成为可能，因为软件解释了内窥镜的横向移动。 我们的第一阶段工作涉及运动跟踪和拼接软件的开发。然后，我们将在体模靶中评估该技术，最后在子宫切除术后立即获得的人类子宫的体外研究中评估该技术。 如果成功，我们设想第二阶段的工作重点是开发和测试临床级原型。我们的长期目标是为妇科医生提供一个基于办公室的工具来目视检查子宫内膜。

DESCRIPTION (provided by applicant): Hysteroscopic imaging is an important diagnostic tool for the evaluation of the uterus. However, manipulation of the scope to serially visualize the entire endometrial cavity is technically challenging and is subject to a steep learning curve. This motivated our company to design the Endometrioscope, which uses an omni-directional tip, dewarping software, and a servomotor to produce a single visual map of the endometrium in an automated fashion. We now propose to investigate the use of visual motion tracking to create a mosaic of the endometrial cavity. This technology will offer three key advantages. First, we will be able to compensate for motion beyond simple linear displacement of the lens (such as rotation, deformation and scaling). Second, the need for a bulky mount and servomotor will be eliminated as the software tracks the free hand movement of the scope. Third, imaging of the uterine horns will become possible as lateral movement of the scope is interpreted by the software. Our Phase I effort involves development of the motion tracking and mosaicing software. We will then evaluate the technology in a phantom target and finally during an ex-vivo study of human uteri obtained immediately following hysterectomy. If successful, we envision a Phase II effort focused on the development and testing of a clinical grade prototype. It is our long-term goal to provide the gynecologist with an office-based tool to visually investigate the endometrium.