Western Regional Community Clinical Oncology Program

描述（由申请人提供）：大凤凰城CCOP是一个由五家医院组成的联合体，拥有40名研究人员，由首席研究员David King博士领导。King博士和许多研究人员自1982年成立以来一直与CCOP有关。GPCCOP持续的长期目标和具体目标包括：1)通过新建和已建立的研究基地增加临床研究活动；2)参与由其他NCI机制支持的化学预防研究，以增加对GPCCOP人群的服务；4)维护和加强质量保证和药房工具，以支持GPCCOP的累积；5)提供人类受试者保护和最小的研究风险；6)支持“ 2010年健康人”的疾病预防目标，特别是通过以少数民族、妇女和得不到充分服务的人为重点的外联、联系和招聘战略，消除不同人口阶层之间的健康差距。GPCCOP的组织结构要求调查人员、各参与组成组织的医院管理人员和工作人员参与规划和决策。GPCCOP的研究活动和资源在治疗部分和化学预防部分之间平均分配，每个部分都实现了国家癌症研究所制定的累积目标和质量目标。GPCCOP的外展重点是通过社区联系、合作和地理多样性实现少数群体和服务不足群体的目标。通过建立社区和部落伙伴关系，GPCCOP促进了覆盖4万多平方英里和4个县的扩展范围。GPCCOP致力于参与者累积（过去五年中205例治疗和超过1000例化学预防参与者）、质量保证、人类受试者保护和少数群体外展，以及其联盟医院的资源投入，表明其准备继续积极参与NCI的社区临床肿瘤项目。

DESCRIPTION (provided by applicant): The Greater Phoenix CCOP is a consortium of five hospitals with 40 investigators, led by principal investigator, David King, MD. Dr. King and many of the investigators have been associated with the CCOP since its inception in 1982. The continuing long-term goals and specific aims of the GPCCOP include: 1) To increase clinical research activities with new and established research bases; 2) To participate in chemoprevention studies supported through other NCI mechanisms, to enhance offerings to GPCCOP's population; 4) To maintain and enhance quality assurance and pharmacy tools to support GPCCOP accrual; 5) To provide for human subject protection and minimal research risk; and 6) To support the disease prevention objectives of "Healthy People 2010" - in particular, to eliminate health disparities among different segments of the population through outreach, affiliations, and recruitment strategies focusing on minorities, women, and the underserved. GPCCOP's organizational structure requires the involvement of the investigators, hospital administrators from each of the participating component organizations and the staff in planning and policy-making decisions. The research activities and resources are split evenly between the treatment segment and the chemoprevention segment of GPCCOP, with each segment achieving accrual and quality goals established by the National Cancer Institute. GPCCOP's outreach is focused on achieving goals of minority and underserved accrual through community affiliations, collaborations, and geographical diversity. By establishing community and tribal partnerships, GPCCOP facilitates an outreach territory encompassing more that 40,000 square miles and 4 counties. GPCCOP's dedication to participant accrual (205 treatment and more than 1000 chemoprevention participants in the past five years), quality assurance, human subject protection, and minority outreach, as well as the devotion of resources from its consortium hospitals, demonstrate its preparedness to continue its active participation in NCI's Community Clinical Oncology Program.