Maternal depression and child weight: Early pathways

描述（由申请人提供）：儿童超重是我们这个时代最重要的健康问题之一，因为他们给个人生活和整个社会带来了负担。母亲抑郁可能对儿童期超重有重大影响。本申请旨在研究母亲抑郁症和儿童时期体重变化之间的关系，并系统地研究解释这种关系的可能机制。我们建议进行二次数据分析的脆弱家庭（FF）研究和幼儿纵向研究-幼儿园（ECLS-K），收集纵向信息的母亲抑郁症和超重的儿童在儿童的国家样本。在FF研究中，可获得从出生到三岁（三波）的信息（估计N= 2，355），在ECLS-K中，从学前班到五年级（5波）（估计N= 8，818）。在FF研究中，使用DSM-IV重性抑郁障碍筛查（CIDI简表）测量母亲抑郁，在ECLS-K中，使用广泛使用的抑郁量表（ECD-S）的简要版本。拟议分析的具体目的是检查：（一）母亲抑郁症和体重之间的关系，在不同阶段的儿童期;（二）在儿童体重的社会或种族/民族差异的作用，解释利益的关系;和（三）具体的预防/治疗相关的机制，包括不良的饮食习惯和缺乏体育活动，可能占利益的关系。将使用纵向多变量统计回归分析技术和结构方程模型分析数据，控制重要的相关性。了解解释母亲抑郁症和儿童超重之间关系的机制，为预防和治疗儿童肥胖提供了巨大的潜力。鉴于治疗体重问题的有效性有限，阐明这一重要途径将为开发新的预防干预措施提供重要信息。

DESCRIPTION (provided by applicant): Childhood overweight is one of the most important health issues of our times, given their burden to individual lives and society as a whole. It is possible that maternal depression has a significant impact at overweight in childhood. This application aims to examine the relationship between maternal depression and weight change during childhood and systematically investigate possible mechanisms explaining this relationship. We propose to conduct secondary data analysis of the Fragile Families (FF) Study and the Early Childhood Longitudinal Study - Kindergarten (ECLS-K), which collected longitudinal information about maternal depression and overweight in childhood in national samples of children. In the FF study, information is available from birth to three years (three waves) (estimated N=2,355) and in the ECLS-K, from pre-K to 5th grade (5 waves) (estimated N=8,818). Maternal depression was measured, in the FF study, using a screening for DSM-IV major depressive disorder (the CIDI short form), and in the ECLS-K, by a brief version of a widely used depression scale (ECD-S). The specific aims of the proposed analysis are to examine: (I) the relationship between maternal depression and weight during different phases of childhood; (II) the role of social or racial/ethnic disparities in childhood weight in explaining the relationship of interest; and (III) specific prevention/treatment relevant mechanisms, including poor dietary practices and lack of physical activity that may account for the relationship of interest. Data will be analyzed using longitudinal multivariate statistical regression analysis techniques and structured equation modeling, controlling for important correlates. Understanding mechanisms explaining the relationship between maternal depression and overweight in childhood offers great potential to inform prevention and treatment of childhood obesity. Given the limited effectiveness of treatment for weight problems, elucidating this significant pathways will provide important information for developing new preventive interventions.