Proteomic biomarkers for radiation injury and countermeasure efficacy
Proteomic biomarkers for radiation injury and countermeasure efficacy
批准号:
10723267
负责人:
Vijay Singh
金额:
$10.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AnimalsBiologicalBiological MarkersDataDevelopmentDoseExperimental ModelsExposure toGamma RaysIndividualInterleukin-11Molecular TargetPrediction of Response to TherapyProteomicsRadiation InjuriesResearch Project GrantsSamplingSubcutaneous InjectionsTreatment outcomeanalogirradiationnonhuman primatepre-clinicalradiation countermeasureradiation mitigator
中文摘要
本研究项目的总体目标是在非人类灵长类动物(NHP)的临床前实验模型中确定照射的蛋白质组生物标志物。这些数据可以预测长期暴露在γ辐射下的患者的治疗结果。此外,这样的生物标记物可能有助于识别对开发有前景的放射增强剂有用的分子靶点。
英文摘要
The overall objective of this research project is to determine proteomic biomarkers of irradiation in preclinical experimental models of non-human primates (NHP). These data may permit prediction of treatment outcomes for individuals exposed to γ-radiation over the long term. Additionally, such biomarkers may help identify molecular targets useful for the development of promising radiomitigators.
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会议论文
Predicting computations necessary for the decoding of odor mixtures by the olfactory system
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批准号:10397603
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项目类别:
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资助金额:$14.4万
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财政年份:2021
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负责人:Vijay Singh
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依托单位:
Predicting computations necessary for the decoding of odor mixtures by the olfactory system
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批准号:10621161
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项目类别:
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资助金额:$14.4万
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财政年份:2021
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负责人:Vijay Singh
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依托单位:
海外基金