ACTIVITY #3 - ENHANCEMENT OF NEUROGENETICS RESEARCH AT THE INST OF NEUROBIOLOGY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 波多黎各大学医学校园的一个主要长期目标是扩大和改善分子神经科学的环境。为了帮助实现这一目标，该项目将在神经生物学研究所建立一个神经遗传学核心设施(具体目标1)。这一设施将用于加强现有教员的研究能力，并将作为研究所进一步发展的资源。这一目标的一个关键特征将是招募一名神经遗传学家来领导该设施。资金将用于改造实验室空间，获得主要仪器，支持神经遗传学或神经基因组学领域的合作，并用于招聘过程。它们还将被用来发展神经生物学研究所和外部研究人员之间的合作研究团队。分子神经生物学核心设施的运作也将继续(具体目标2)，该设施是根据上一项RCMI倡议设立的。这个设施毗邻正在被提议容纳神经遗传学核心的空间。它已被本提案的参与者广泛使用，并被认为是其研究的重要资产。该研究所的所有分子生物学都以这一设施为中心，预计它也将是神经遗传学研究的重要资源。此外，还将改进研究所与波多黎各以外的研究小组之间的沟通(具体目标3)。这将通过改善互联网连接、视频会议能力以及实施支持与外部科学家合作的机制来实现。综上所述，这些变化将为神经生物学研究所增加强大的新的研究和培训能力，并增强现有的能力。它们还将有助于在当前研究和公共卫生之间建立更好的联系。这些变化是为了应对神经科学研究不断发展的环境所带来的挑战。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A major long-term objective of the University of Puerto Rico Medical Sciences Campus is to expand and improve the environment for molecular neuroscience. To help meet that goal, this project will establish a Neurogenetics Core Facility at the Institute of Neurobiology (Specific Aim 1). This facility will be used to enhance the research capabilities of the present faculty and will serve as a resource for the further development of the Institute. A key feature of this aim will be to recruit a neurogeneticist to head the facility. Funds will be used to remodel lab space, obtain major instrumentation, support collaborations in the areas of neurogenetics or neurogenomics, and for the recruitment process. They will also be used to develop collaborative research teams between the Institute of Neurobiology and outside researchers. The operation of the Molecular Neurobiology Core Facility, established under the last RCMI initiative, will also be continued (Specific Aim 2). This facility is adjacent to the space that is being proposed to house the Neurogenetics Core. It has been used extensively by the participants in this proposal and is considered a vital asset for their research. All molecular biology at the Institute centers on this facility, and it is anticipated that it will also be an essential resource for investigation in neurogenetics. In addition, improvements will be made in communications between the Institute and research groups outside of Puerto Rico (Specific Aim 3). This will be accomplished by improving the internet connections, video conferencing capabilities and by implementing a mechanism to support collaborations with outside scientists. Taken together, these changes will add powerful new research and training capabilities to the Institute of Neurobiology, as well as enhance existing capabilities. They will also help create better links between current research and public health. These changes are required to meet the challenges of an evolving environment for Neuroscience research.