Nephrology and Hypertension Training Grant

超出所提供的空间。这是一个关于肾病和高血压博士后研究培训计划的建议。目标是培养医生和科学家对肾脏和高血压疾病以及作为正常和异常肾功能或血压调节基础的基础生物学进行独立研究。我们强调应用前沿的基础研究技术，以健康相关的肾脏和高血压疾病，包括血压和容量稳态，受体调节，血管生理学，药理学和血管生成，细胞内信号，氧化应激，性别和妊娠对血管功能的影响，分子遗传学和肾脏血管活性因子之间的相互作用的肾脏机制的研究。候选人将拥有MD和/或PhD。医生将完成内科或儿科的临床培训，大多数将接受肾脏病学的临床专科培训。研究培训计划将持续2年，期间将严格限制患者护理活动。候选人将由全体教师根据在研究和学术肾脏学，面试，推荐信和过去的表现所述的职业目标进行选择。候选人的进展将由项目主任和联合主任，个别教师导师评估，由培训教师审查和正式演示文稿和书面进度报告的审查。所有培训将在乔治敦大学医学中心进行，在来自医学，儿科学，药理学，生理学和分子遗传学系的一个具有凝聚力和高度协作性的培训教师小组的实验室中进行。核心教师是NIH计划项目补助金的Pi，从而进行由核心设施支持的研究。培训和支持教师来自基础和临床部门。主要教员是新成立的心血管肾脏研究所的成员。这提供了一个有凝聚力和协作的研究环境。为了利用这些特殊资源，并在该赠款方案头5年成功的基础上，我们建议将受训人员人数从4人增加到6人。其目的是培养博士后科学家，除了医生，在学术肾病和高血压计划的职业生涯。性能现场=

EXCEED THE SPACE PROVIDED. This is a proposal for a research training program for post-doctoral trainees in Nephrolbgy and Hypertension. The goal is to prepare physicians and scientists to undertake independent investigation in renal and hypertensive disorders and in the basic biology which underlies normal and aberrant kidney function or blood pressure regulation. We emphasize application of cutting edge basic research techniques to health related problems of renal and hypertensive disease that include studies of renal mechanisms of blood pressure and volume homeostasis, receptor regulation, vascular physiology, pharmacology and angiogenesis, intracellular signaling, oxidative stress, effects of gender and pregnancy on vascular function, molecular genetics and interactions between vasoactive factors in the kidney. Candidates will have the MD and/or PhD. Physicians will have completed clinical training in either internal medicine or pediatrics and most will undertake clinical subspecialty training in nephrology. The research training program will be for 2 years, during which patient care activities will be strictly limited. Candidates will be selected by the entire faculty based upon stated career goals in research and academic nephrology, interviews, letters of recommendation, and past performance. Progress of candidates will be assessed by the program director and co-director, individual faculty preceptors, review by the training faculty and review of formal presentations and written progress reports. All training will be carried out at Georgetown University Medical Center, in the laboratories of a cohesive and highly collaborative group of training faculty drawn from the Department of Medicine, Pediatrics, Pharmacology, Physiology, and Molecular Genetics. The core faculty are the Pi's of an NIH Program Project Grant and thereby undertake research supported by core facilities. The training and support faculty are drawn from basic and clinical departments. The key faculty are members of the newly formed Cardiovascular Kidney Institute. This provides a cohesive and collaborative research environment. To utilize these special resources and to build on the successes of the first 5 years of this grant program, we propose to expand the number of trainees from 4 to 6. The aim is to train post-doctoral scientists, in additional to physicians, for a career in academic nephrology and hypertension program. PERFORMANCE SITE ========================================Section End===========================================