IDENTIFICATION, SURVEILLANCE AND CONTROL OF VECTOR - BORNE AND ZOONOTIC INFECTIOU

描述(申请人提供)：乌干达，像撒哈拉以南非洲的大部分地区一样，正处于公共卫生危机之中。乌干达大量的传染病、病媒和人畜共患疾病肆虐，阻碍了社会和经济发展，给人类带来了许多苦难。在这份提案中，乌干达病毒研究所描述了一个调查和控制乌干达媒介传播和人畜共患疾病的多年项目。为了实现这一长期目标，这项研究建议将侧重于评估媒介传播的疾病和人畜共患病在乌干达造成的疾病负担，描述与媒介传播的疾病和人畜共患病有关的乌干达的地方性和流行性疾病参数，开发方案和技术以减少乌干达媒介传播的疾病和人畜共患病的发病率和死亡率，确定乌干达媒介传播的疾病和人畜共患病的宿主和媒介的特征，从乌干达获得不同的细菌和病毒分离株档案，最后制定和评估在现场条件下经济上可持续的控制策略。

DESCRIPTION (provided by applicant): Uganda, like much of sub-Saharan Africa, is in the midst of a public health crisis. The great number of infectious, vector-borne and zoonotic diseases rampant in Uganda has caused a retardation of social and economic development and much human suffering. In this proposal, the Ugandan Virus Research Institute describes a multi-year project investigating and controlling vector-borne and zoonotic disease in Uganda. In order to achieve this long-term aim, this research proposal will focus on assessing the disease burden caused by vector-borne and zoonotic diseases in Uganda, describing the enzootic and epizootic parameters associated with vector-borne and zoonotic diseases in Uganda, developing programs and technology to reduce morbidity and mortality due to vector-borne and zoonotic diseases in Uganda, characterize the reservoir hosts and vectors of vector-borne and zoonotic diseases in Uganda, acquiring a diverse archive collection of bacterial and viral isolates from Uganda and lastly, developing and evaluating economically sustainable control strategies under field conditions.