Health and Literacy in Child and Adult Assessment(RMI)

描述(由申请人提供)：北卡罗来纳大学教堂山分校及其合作伙伴提出的成为PROIS初级研究站点的建议：(1)8-17岁儿童的PRO评估(独立项目)；(2)低识字率人群中英语和西班牙语的发展和测试项目；以及(3)变量的严格评估(例如，许多方面的功能能力或坚持治疗)，最恰当的概念是二元(例如，妻子-丈夫，父母-孩子)，而不是个人。我们的独立项目将(1)使用IRT来评估PedsQLTM4.0在4个核心领域(身体、情绪、社会、学校/认知)和哮喘特定领域的8,000名儿童的项目参数，以这一广泛使用的工具作为儿科题库的起点，(2)开发新项目并收集数据，在北卡罗来纳州和德克萨斯州的1,060名儿童中，使用IRT来估计项目参数，(3)开发和试点测试CAT工具，并使用它来调查北卡罗来纳州和德克萨斯州的375名儿童。我们的长期目标是开发CAT来评估广泛的慢性儿童疾病临床研究中的专业人员。然而，最初的数据收集将在哮喘儿童和健康儿童中进行。 我们的扫盲网络项目建议开发一种方法来创建和测试英语和西班牙语的PRO项目，这些项目在各种语言和识字水平上都能一致地发挥作用。我们将在以下方面发挥领导作用：(1)评估患者识字能力，(2)测试低识字率人群的项目理解力，(3)制定战略，开发低识字率人群能够理解的新项目，(4)测试英语或西班牙语人群不同样本中的所有项目，以评估代表所有识字水平的不同种族多元化患者群体中语言或识字率的不同项目功能。我们的二元评估网络项目建议(1)明确主要是人际关系的健康变量，(2)确定这些变量的现有衡量标准并评估其有效性，(3)修改未能以反映人际关系性质的方式评估人际关系过程的衡量标准，(4)协助网络收集有关修改后的衡量标准的数据并评估其有效性。

DESCRIPTION (provided by applicant): "Health and Literacy in Child and Adult Assessment," a proposal to become a PROMIS Primary Research Site by The University of North Carolina at Chapel Hill and its partners, addresses 3 important problems in using computer adaptive testing (CAT) to measure patient-reported chronic diseases outcomes (PROs) in clinical research: (1) PRO assessment in children 8-17 years of age (Independent Project), (2) Development and testing items in low literacy populations in English and Spanish, and (3) Rigorous assessment of variables (e.g., many aspects of functional capacity or adherence to treatment) most appropriately conceptualized as dyadic (e.g., wife-husband, parent-child) rather than individual. Our Independent Project will (1) use IRT to evaluate item parameters for the PedsQLTM4.0 in 8,000 children in 4 core domains (physical, emotional, social, school/cognitive) and an asthma-specific domain, taking this widely used instrument as a starting point for a pediatric item bank, (2) develop new items and collect data in 1,060 children in North Carolina and Texas, using IRT to estimate item parameters, (3) develop and pilot test a CAT tool and use it to survey 375 children in NC and Texas. Our long-term objective is to develop CAT to assess PROs in clinical research across a wide range of chronic childhood diseases. However, this initial data collection will be in children with asthma and in healthy children. Our Network Project on literacy proposes developing a methodology for creating and testing PRO items in English and Spanish that function consistently across languages and literacy levels. We will provide leadership for (1) assessing patient literacy, (2) testing item comprehension in low literacy populations, (3) devising a strategy to develop new items that can be understood by people with low literacy, (4) testing all items in diverse samples of English- or Spanish-speaking people to evaluate differential item functioning by language or literacy in our large ethnically diverse patient population representing all literacy levels. Our Network Project on dyadic assessment proposes (1) specifying health variables that are largely interpersonal, (2) identifying existing measures of these and assessing their validity, (3) modifying measures that fail to assess interpersonal processes in a way that captures their interpersonal nature, (4) assisting the Network in collecting data on the modified measures and assessing their validity.