A rapid, low-cost, point-of-consumption detection device for gluten in food.

项目总结 过敏护身符致力于通过一种快速、便携、 面筋消耗点检测仪。面筋蛋白构成了一种重大的且不断增长的风险 数以百万计的美国人患有面筋相关疾病，症状从腹部到腹部 痛得要死。面筋相关疾病患者在消费时面临更高的焦虑和恐惧 由他人配制的食品由于交叉污染、信息不实等原因， 能够准确检测含面筋食物和配料的便携式设备将是 对现状的巨大改善。拟议中的技术将作为补充 为用户提供了一种管理工具，使他们能够直接品尝他们的食物以发现不需要的食物 并为其他人准备的食品是安全的提供了额外的一层保证。 第一阶段工作的目标是证明低成本电化学技术的可行性。 能够检测复杂食品中面筋的传感平台。为实现这一目标，第一阶段 包括以下具体目标：1)开发选择性检测的传感平台 面筋；2)针对一系列不同的全食验证传感器。首席调查员 在这个项目上，Dan Sundhoro博士在生物结合和生物连接的设计方面拥有丰富的经验 复杂背景下的传感平台。过敏性爱茉莉公司专注于过敏性检测和 相关技术，并开展市场研究并建立战略合作伙伴关系 并计划将该设备商业化。该公司将监督 该项目的可行性研究和商业化方面。 与第二阶段工作的关系：成功完成第一阶段目标将使我们能够继续 第二阶段资金，将用于进一步优化传感器技术的灵敏度和 并促进该设备的商业化，以供消费者使用。过敏护身符会 利用其现有的投资者网络和董事会，包括过敏症专家、医生、 医疗保健高管、科学家、经验丰富的企业家和广泛的人脉 各行各业将有助于确保向市场的成功过渡。成功的商业化 将产生一种具有高市场价值的产品，可以帮助防止数千起紧急情况 每年的房间访问量，并有可能拯救生命。

PROJECT SUMMARY Allergy Amulet, Inc. is committed to providing greater food transparency with a rapid, portable, point-of-consumption gluten detection device. Gluten poses a significant and growing risk for the millions of Americans living with gluten-related disorders, with symptoms ranging from abdominal pain to death. Sufferers of gluten-related disorders face higher anxiety and fear when consuming food products prepared by others due to cross-contamination, misinformation, etc. A reliable, portable device capable of accurately detecting gluten-containing foods and ingredients would be a vast improvement on the status quo. The proposed technology will serve as a supplemental management tool for users by enabling them to directly sample their food for unwanted ingredients and providing an additional layer of assurance that foods prepared by others are safe. The objective of this Phase I effort is to demonstrate the feasibility of a low-cost electrochemical sensing platform capable of detecting gluten in complex foods. Toward this objective, Phase I encompasses the following Specific Aims: 1) develop a sensing platform for selective detection of gluten; 2) validate the sensors against a diverse array of whole foods. The Principal Investigator on this project, Dr. Dan Sundhoro, has extensive experience in the design of bioconjugation and sensing platforms in complex backgrounds. Allergy Amulet, Inc. focuses on allergy detection and related technologies, and has carried out market research and established strategic partnerships within the allergy community and plans to commercialize the device. The company will oversee the feasibility study and commercialization aspects of the project. Relationship to Phase II Work: Successful completion of Phase I aims will allow us to pursue Phase II funding, which will be used to further optimize the sensor technology for sensitivity and specificity and advance the commercialization of the device for consumer use. Allergy Amulet will leverage its existing investor network and board of directors, including allergists, doctors, healthcare executives, scientists, seasoned entrepreneurs, and extensive connections across myriad industries will help ensure a successful transition to market. Successful commercialization will result in a product with high market value that could help prevent thousands of emergency room visits per year and potentially save lives.