Administrative Core - The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging Infectious Diseases at Northwestern University (C-THAN)

摘要-行政(管理)核心 艾滋病毒/艾滋病和新发传染病护理点技术创新中心 西北大学疾病研究中心(C-Than)将成为技术研发的重要合作伙伴 NIBIB护理点技术研究网络(POCTRN)中的中心(TRDC)专注于其使命 通过增强优势互补的模式促进诊断技术创新 在技术平台、临床、监管和商业化方面建立多学科合作伙伴关系 特别侧重于艾滋病毒/艾滋病和中低收入者新发传染病的领域 国家(LMIC)。C-Than的结构将由护理地点的科学和技术专门知识组成 (POC)和基于家庭的诊断以及临床研究设计和站点，以促进识别和 将使能技术整合到设备中，以满足艾滋病毒/艾滋病的特定临床需求 新出现的传染病。C-Than将包括四个核心：管理、技术、临床、 和传播。重点将通过建立以下内容来针对特定的技术领域 技术工作组(WG)：1)分子，2)横向流动，3)合成生物学，4)产品工程。 管理核心将提供适当的领导和结构来管理C-Than的许多方面， 一个庞大而复杂的TRDC。管理核心将作为C-Than的管理组件 负责领导该中心的组织、治理、POCTRN内外的合作， 沟通和持续改进活动的质量和效率。C-Than将被指导 医学博士，医学博士，公共卫生硕士，生物医学工程师(BME)和具有专业知识的医生 在传染病和公共卫生领域拥有超过20年的艾滋病毒临床研究经验和 新兴传染病，罗伯特·墨菲医学博士，传染病专业研究医生，曾 萨利·麦克福尔在非洲工作了22年以上，她是一名生物医学工程师和 为非洲开发POC医疗设备。他们将得到C-Than指导委员会的协助，该委员会 将提供对C-Than职能的科学和行政监督，包括审查和选择 获得分奖资助的项目。C-Than的主要合作机构包括西北大学 (主要合作伙伴)；开普敦大学、威特沃特斯兰德大学(WITS)、斯泰伦博什大学、 拉各斯大学、伊巴丹大学、乔斯大学、穆亨比利健康与联合科学大学 (MUHAS)、科学大学、DES Technologies et Des Technologies de Bamako(USTTB)和 谢赫·安塔迪奥普大学(UCAD)。C-Than财团将在其20年历史的基础上 与尼日利亚、马里、塞内加尔、坦桑尼亚和尼日利亚的主要合作伙伴进行基础设施开发和研究培训 南非。

SUMMARY – ADMINISTRATIVE (ADMIN) CORE The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging Infectious Diseases at Northwestern (C-THAN) will be a vital partner as a Technology Research and Development Centers (TRDC) in the NIBIB Point-of-Care Technologies Research Network (POCTRN) focusing its mission to catalyze innovation in diagnostic technologies through a model that enhances complementary strengths to build multidisciplinary partnerships across technology platforms, clinical, regulatory and commercialization domains with a specific focus on HIV/AIDS and emerging infectious diseases in low- and middle-income countries (LMICs). The structure of C-THAN will consist of scientific and technology expertise in point-of-care (POC) and home-based diagnostics along with clinical study design and sites to facilitate the identification and integration of enabling technologies into devices that address the specific clinical needs of HIV/AIDS and emerging infectious diseases. C-THAN will be comprised of four Cores: Administrative, Technology, Clinical, and Dissemination. An emphasis will be directed to specific technology domains by establishing the following technology working groups (WG): 1) molecular, 2) lateral flow, 3) synthetic biology, and 4) product engineering. The Admin Core will provide the appropriate leadership and structure to manage the many facets of C-THAN, a large and complex TRDC. The Admin Core will serve as the managing component of C-THAN that is charged with leading the organization, governance of the center, collaboration within and outside POCTRN, communication and continuous quality improvement and efficiency of the activities. C-THAN will be directed by the MPIs, Drs. Chad Achenbach, MD, MPH, a biomedical engineer (BME) and medical doctor with expertise in infectious diseases and public health with over 20 years of experience in clinical research on HIV and emerging infectious diseases, Robert Murphy, MD, an infectious diseases trained research physician who has been working in Africa for more than 22 years, Sally McFall, PhD a biomedical engineer and expert in developing POC medical devices for Africa. They will be assisted by the C-THAN Steering Committee which will provide scientific and administrative oversight of C-THAN functions including review and selection of projects to receive sub-award funding. Key partner institutions of C-THAN include Northwestern University (lead partner); University of Cape Town, University of the Witwatersrand (WITS), Stellenbosch University, University of Lagos, University of Ibadan, University of Jos, Muhimbili University of Health and Allied Sciences (MUHAS), Université des Sciences, des Techniques et des Technologies de Bamako (USTTB), and the University Cheikh Anta Diop (UCAD). The C-THAN consortium will build upon its 20-year history of infrastructure development and research training with key partners in Nigeria, Mali, Senegal, Tanzania, and South Africa.