Characterizing the influence of COVID-19, Racial Trauma, and Social Networks on CV Health Factors among young Black women in the South

摘要 年轻人中与心血管相关的发病率和死亡率正在上升， 与白人女性相比，年轻黑人女性的性别差异更为明显。心理社会因素，如 种族主义、感受到的压力和缺乏社会支持导致了种族不平等 心血管疾病。心理社会因素也会对身体活动产生负面影响 其他对最佳心血管健康(CVH)至关重要的行为，但很少有干预措施关注 在这些关键因素上。最近，新冠肺炎大流行期间的社会动荡，如 随着关注美国种族主义的事件激增，放大了心理社会 许多黑人女性都经历过压力。与此同时，社会距离的要求 流行病可能破坏了社交网络，扰乱了支持系统和典型的应对措施 战略。迫切需要文化上量身定做的生物行为干预措施来缓解 研究表明，与新冠肺炎相关的心血管疾病发病率将会上升 大流行，但首先，评估大流行和种族压力对CVH的影响 行为是必要的，社交网络上的数据也是严格的。 这项拟议的研究建立在现有的针对黑人成年人的随机二元干预的基础上 因感染新冠肺炎而住院(R01NR020127)。通过关注年轻的黑人女性 (18-39岁)有高血压或其他心血管疾病危险因素者为新冠肺炎 幸存者但没有住院，我们将提供来自非住院患者的对比数据 一群人。我们将使用并行三角测量混合方法设计来评估 健康的结构性和社会决定因素以及新冠肺炎大流行对生活质量和 CVH行为(例如，体力活动、饮食和睡眠)(目标1)。此外，我们还将描述 年轻黑人女性的社交网络，包括压力经历的处理， 压力来源，以及未来网络/二元干预的感知机会(目标2)。 拟议的研究将通过分析已经存在的变量来为家长研究做出贡献 收集(例如，社会支持)，并提议在社交网络上收集新的数据，包括 二元关系。这项研究是新颖的，它的重点是预防心血管疾病的年轻人和 严格评估社交网络中的压力应对，包括种族主义，使用量化 为未来量身定做的生物行为干预提供信息的方法。

Abstract Cardiovascular-related morbidity and mortality among young adults are rising, and disparities are stark among young Black women compared to White women. Psychosocial factors, such as racism, perceived stress, and lack of social support, contribute to racial inequities in cardiovascular disease. Psychosocial factors also negatively influence physical activity and other behaviors essential for optimal cardiovascular health (CVH), but few interventions focus on these critical factors. Most recently, the social upheaval during the COVID-19 pandemic, as well as a surge in events placing a spotlight on racism in America, amplified the psychosocial stress experienced by many Black women. At the same time, social distancing required by the pandemic may have frayed social networks, disrupting support systems and typical coping strategies. There is a pressing need for culturally tailored, biobehavioral interventions to mitigate what research suggests will be an uptick in cardiovascular disease related to the COVID-19 pandemic, but first, an assessment of the impacts of the pandemic and racial stressors on CVH behaviors is needed, and rigorous data on the social networks. The proposed study builds on an existing randomized dyadic intervention for Black adults hospitalized with a COVID-19 infection (R01NR020127). By focusing on young Black women (ages 18 – 39) with hypertension or other cardiovascular disease risk factors who are COVID-19 survivors but were not hospitalized, we will provide comparison data from a non-hospitalized cohort. We will use a concurrent triangulation mixed methods design to assess the influence of structural and social determinants of health and the COVID-19 pandemic on quality of life and CVH behaviors (e.g., physical activity, diet, and sleep) (aim 1). In addition, we will characterize the social networks of young Black women, including the processing of stressful experiences, sources of strain, and perceived opportunities for future network/dyadic interventions (aim 2). The proposed research will contribute to the parent study by analyzing variables already being collected (e.g., social support) and proposing new data collection on social networks, including dyadic relationships. This study is novel in its focus on CVD prevention in young adulthood and rigorous assessment of stress coping, including racism, within social networks using quantitative methods to inform future tailored, biobehavioral interventions.