CELL IMAGING SHARED RESOURCES

先进的数字成像显微镜是糖尿病相关研究的有力工具， 有效使用和正确维护设备的成本和专业知识超出了大多数公司的资源， 个别实验室我们很幸运在范德比尔特有一个领先的设施成像糖尿病相关 因此，在下一个资助周期，DRTC将继续支持细胞成像 资源共享资源，以便DRTC附属研究者能够获得其专业知识， 以较低的价格提供大量设施。细胞成像共享资源的总体目标是维护 全方位的现代显微镜和数字成像能力，以实现和加速研究， 否则会在数量和质量上减少。细胞成像核心促进糖尿病研究， 范德比尔特通过这些目标：1）获取和保持最先进的光学和EM成像 技术; 2）培训，协助和鼓励DRTC附属研究人员将光学，EM和 体内成像技术纳入他们的研究;和3）开发新的成像技术，这将是有用的， 糖尿病研究重要的是，该设施还将继续开发新兴的光学和电子成像 糖尿病研究社区的技术。2000年至2005年间，细胞成像共享 资源在资源和使用量方面都经历了大约500%的增长。自上次DRTC拨款以来 更新后，细胞成像共享资源大大增加了容量和先进的成像 能力的核心地区对先进的专业显微镜服务的需求仍然强劲。更 超过75个DRTC附属研究小组（包括42个现有成员）使用了细胞成像共享 在过去的五年里，这些研究人员已经产生了100多个同行评审 使用成像资源设备和/或协助的论文。此共享资源是范德比尔特 共享设施系统，提供高效的计费系统以及对 核心细胞成像资源共享资源将继续提供必要的服务， DRTC附属研究人员的研究在下一个资助周期。

Advanced digital imaging microscopy is a powerful tool for diabetes-related research, but the equipment costs and expertise to efficiently use and properly maintain the equipment is beyond the resources of most individual labs. We are fortunate at Vanderbilt to have one of the leading facilities for imaging diabetesrelated processes, and thus, in the next funding cycle, the DRTC will continue to support the Cell Imaging Resource Shared Resource so that DRTC-affiliated investigators will have access to its expertise and substantial facilities at a reduced rate. The overall goal of the Cell Imaging Shared Resource is to maintain the full range of modern microscopy and digital imaging capabilities to enable and accelerate research that would otherwise be reduced in quantity and quality. The Cell Imaging Core facilitates diabetes research at Vanderbilt through these objectives: 1) acquire and maintain state-of-the art optical and EM imaging technology; 2) train, assist, and encourage DRTC-affiliated investigators to incorporate optical, EM, and in vivo imaging technologies into their research; and 3) develop new imaging technologies that will be useful for diabetes research. Importantly, this facility continues to also develop emerging optical and electron imaging techniques for the diabetes research community. Between 2000 and 2005 the Cell Imaging Shared Resource experienced approximately 500% growth in both resources and usage. Since the last DRTC grant renewal, the Cell Imaging Shared Resource has greatly increased capacity and advanced imaging capabilities. The demand for advanced, specialized microscopy service in the core remains strong. More than 75 DRTC-affiliated research groups (including 42 current members) have used the Cell Imaging Shared Resource during the last five years, and these investigators have generated more than 100 peer-reviewed papers using imaging resource equipment and/or assistance. This Shared Resource is part the Vanderbilt shared facilities system, which provides an efficient billing system and oversight and governance for the core. The Cell Imaging Resource Shared Resource will continue to provide essential services that support the research of DRTC-affiliated investigators in the next funding cycle.