Metformin in Gestational Diabetes: follow-up of mothers and offspring: body composition, insulin resistance, development

患有妊娠期糖尿病的妇女所生的孩子日后患肥胖症和糖尿病的风险更高。这项研究将有助于评估在怀孕期间给这些妇女服用廉价的口服糖尿病药物二甲双胍而不是注射胰岛素是否可以安全地降低这种风险，测量2岁和5岁儿童的生长、脂肪和血糖-胰岛素，以及评估母亲。如果是这样的话，这种治疗可能有助于减轻全球范围内与肥胖相关的疾病的负担。

Children born to women with gestational diabetes are at increased risk of later obesity and diabetes. This study will help to assess if giving such women during their pregnancy the cheap oral diabetes drug metformin rather than insulin injections can safely reduce this risk, measuring growth, fatness and blood glucose-insulin in the children at 2 and 5 years of age, as well as assessing the mothers. If so, such treatment might help to reduce the worldwide burden of disease related to obesity.