Antioxidants vitamin C and vitamin E for the prevention of pre-eclampsia - a randomised controlled trial

抗氧化剂维生素 C 和维生素 E 预防先兆子痫 - 一项随机对照试验

• 批准号: nhmrc : 207744
• 负责人: A/Pr Ross Haslam
• 金额: $ 46.46万
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2002
• 资助国家: 澳大利亚
• 起止时间: 2002-01-01 至 2004-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/antioxidants-vitamin-c-controlled-trial/82432
• 关键词: Antioxidants; vitamin; prevention; pre; eclampsia

Women who develop hypertension in pregnancy have a higher risk of complications in pregnancy and their babies are often born smaller than average and earlier. An initial trial to women at high risk of pre-eclampsia suggest that vitamin C and vitmin E supplements may decrease both reduce the risk of developing hypertension in pregnancy and the risk of the infant being born small for dates. These encouraging results need assessment in the Australian population. This study assesses the value of women taking vitamin C and vitamin E supplements during the antenatal period to decrease the risk of developing hypertension during pregnancy and poor fetal growth. Such an easy and inexpensive therapy, if effective, would be an important advance.

在怀孕期间患高血压的妇女在怀孕期间患并发症的风险更高，她们的婴儿往往比平均年龄小，出生时间也更早。对先兆子痫高风险妇女的初步试验表明，维生素C和维生素E补充剂可能会降低妊娠期高血压的风险和婴儿出生日期小的风险。这些令人鼓舞的结果需要在澳大利亚人口中进行评估。这项研究评估了妇女在产前服用维生素C和维生素E补充剂以降低妊娠期高血压和胎儿生长不良风险的价值。这种简单而廉价的疗法如果有效，将是一个重要的进步。