CORE--DATA MANAGEMENT AND STATISTICS

DMSC将提供生物统计学、数据处理、数据库编程、研究方法和计算机硬件和软件方面的专业知识，以支持该中心的项目和国家阿尔茨海默病协调中心（NACC）的多中心合作活动。该核心将鼓励和促进研究人员之间的合作和跨项目的信息共享，帮助当地研究人员利用计算资源，监督数据库和执行数据质量活动，提供与NACC互动的接口，并作为集中的生物统计和数据分析资源。该模型是DMSC（该中心的中央数据处理资源）与项目调查员、核心主管和合作者（他们在分析自己的措施方面具有相当的专业知识）之间的共同责任之一。DMSC是 负责ADRC数据库，该数据库已被学员、国际学者和初级教师用于解决有关AD和其他痴呆症的行为变化的问题，以在1999-2002年的当前资助期内产生36篇论文。灾害管理服务中心将继续提供所有数据输入、备份、文件和其他数据库服务，并将及时和准确地向国家核事故协调委员会和其他外部机构提交资料。将向研究人员提供先进的生物统计和方法支持，以帮助规划和执行数据分析，并协助设计和实施新的研究项目。核心小组成员将参加对ADRC试点研究的审查。青年科学家的发展将通过教学介绍和对研究项目的个别指导来完成。

The DMSC will provide expertise in biostatistics, data processing, database programming, research methodology and computer hardware and software to support the Center's projects and the multi-center collaborative activities of the National Alzheimer's Coordinating Center (NACC). The Core will encourage and facilitate collaborations among researchers and the sharing of information across projects, help local investigators make use of computing resources, oversee the database and perform data quality activities, provide the interface for interactions with the NACC, and serve as a centralized biostatistical and data analysis resource. The model is one of shared responsibilities between the DMSC, which is the centralized data processing resource in the Center, and the project investigators, core chiefs, and collaborators who have considerable expertise in analysis of their own measures. The DMSC is responsible for the ADRC database, which has been used by trainees, international scholars, and junior faculty to address questions regarding behavioral changes in AD and other dementias to produce 36 papers in the current grant period 1999-2002. The DMSC will continue to perform all data entry, backup, documentation and other database services, and will make timely and accurate submissions to NACC and other external agencies. Sophisticated biostatistical and methodological support will be provided to researchers to help in planning and execution of data analyses and to aid in the design and implementation of new research projects. Members of the Core will participate in review of ADRC pilot studies. Development of young scientists will be accomplished through didactic presentations and individual mentoring on research projects.