Microevolution and transmission of MRSA in a hospital setting

多重耐药金黄色葡萄球菌(MRSA)会导致医院获得性感染，并导致不必要的疾病和过高的医疗费用。如果没有一个快速、简单的指纹识别系统，就很难确定不同的菌株是如何传播的，哪些最有可能导致疾病。我们已经开发了一种，我们将使用它来鉴定最成功的�MRSA菌株。然后，我们将对它们的整个基因组进行测序，以确定它们为什么会成功地进行�，从而设计出对抗它们的方法。

Multi-drug resistant Staphylococcus aureus (MRSA) cause hospital-acquired infections and are responsible for unnecessary illness and excess health costs. It is hard to identify how different strains spread and which are most likely to cause disease, without a rapid, simple fingerprinting system. We have developed one, which we will use to identify the most _successful� MRSA strains. Then we will sequence their whole genomes, to determine why they are _successful� to devise ways to combat them.