The true burden of nosocomial staphylococcal disease: Genomic markers of transmission of methicillin-sensitive and –resistant Staphylococcus aureus

医院内葡萄球菌疾病的真正负担：甲氧西林敏感和耐药金黄色葡萄球菌传播的基因组标记

• 批准号: nhmrc : 1065908
• 负责人: Dr Matthew O'Sullivan
• 金额: $ 55.35万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/true-burden-nosocomial-staphylococcus-aureus/455208
• 关键词: true; burden; nosocomial; staphylococcal; disease

Staphylococcus aureus is the leading cause of hospital infection, but previous studies have only focused on the 30% caused by resistant strains (MRSA). We will trace the spread of all Staphylococcus strains in hospitals using DNA fingerprinting. This will enable us to determine why patients catch this infection, permitting interventions to reduce hospital infection. We will also examine the genomes of these bacteria to look for markers of transmission and adaptation to the hospital environment.

金黄色葡萄球菌是医院感染的主要原因，但之前的研究仅关注由耐药菌株（MRSA）引起的30%。我们将使用 DNA 指纹识别技术追踪医院中所有葡萄球菌菌株的传播情况。这将使我们能够确定患者感染这种感染的原因，从而采取干预措施减少医院感染。我们还将检查这些细菌的基因组，以寻找传播和适应医院环境的标记。