PEDIATRIC LATE OUTCOMES PROTOCOL

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是跟踪目前或以前参加过儿科ACTG治疗围产期或药物研究的儿童和青少年，以寻找治疗在生长、神经和神经心理功能、长期存活和生活质量方面的任何晚期后果。以下是与儿科干预相关的几个关键假设，该晚期结局协议计划解决这些假设。此外，还预计在该方案中收集的纵向数据将使儿科ACTG的研究人员能够回答他们所参与的围产期方案中具体治疗的其他研究问题和假设。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to follow children and adolescents who are currently enrolled in or were previously enrolled in pediatric ACTG treatment perinatal or drug research studies to look for any late consequences of therapy in growth, neurologic and neuropsychologic function, long term survival, and quallity of life. There are several key hypotheses listen below that this late outcomes protocol plans to address in relation to pediatric interventions. In addition, it is also anticipated that the longitudinal data gathered in this protocol will enable investigators in the pediatric ACTG to answer other research questions and hypotheses specific to treatment in perinatal protocols in which they are involved.