NONPHARMACOLOGICAL TREATMENT OF COMORBID ANXIETY AND HYPERTENSION

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 高血压和焦虑是许多老年人面临的两个问题，并具有显著的健康相关后果。 超过60%的老年人患有高血压，高达40%的老年人有焦虑症状。 高血压和焦虑常为共病。 尽管药物治疗已证明在降低血压方面有效，但仍有大量人群的血压仍然不受控制。 同样，在老年人中，包括焦虑在内的心理健康问题往往未被发现和治疗，导致生活质量下降。 然而，还没有人研究过治疗高血压和焦虑症共病的疗效。 因此，本建议的目的是测试辅助非药物干预联合降低血压和焦虑症状。干预包括呼吸，一种通过延长呼气来调节呼吸的设备。 将32名患有轻度1期不受控制的高血压（SBP 140-159 mm Hg）和焦虑症状的老年人（≥ 65岁）随机分配至两种情况之一：非药物治疗组（ResPerate）和对照组。 这项研究的结果将用于进行一项更大规模的非药物干预共病焦虑和高血压的试验。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hypertension and anxiety are two problems that many older adults face and that have significant health-related consequences. Over 60% of older adults have hypertension and up to 40% experience symptoms of anxiety. Hypertension and anxiety are frequently comorbid conditions. Although pharmacological treatments have demonstrated efficacy in reducing blood pressure, there is still a large population whose blood pressure remains uncontrolled. Similarly, among older adults, mental health problems, including anxiety, frequently go undetected and untreated, resulting in poorer quality of life. However, no one has examined the efficacy of a treatment for comorbid hypertension and anxiety. Thus, the purpose of this proposal is to test an adjuvant nonpharmacological intervention for the combined reduction of blood pressure and anxiety symptoms. The intervention consists of ResPerate, a device that regulates breathing by prolonging exhalation. Thirty two older adults (greater than or equal to 65 years) with mild stage 1 uncontrolled hypertension (SBP 140-159 mm Hg) and symptoms of anxiety will be randomized into one of two conditions: nonpharmacological treatment group (ResPerate) and control group. The results of this study will be used to conduct a larger trial of nonpharmacological interventions for comorbid anxiety and hypertension.