FMRI INVESTIGATION OF EXPECTANCY ON AA

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 区分针灸和安慰剂针灸一直是方法论上的挑战。我们建议使用定量脑成像方法来研究针刺镇痛和安慰剂镇痛的机制以及它们之间的相互关系。一种经过测试的诱导高期望和低期望的方法将与针刺止痛和假针刺止痛相结合，创建真针和假针刺的2×2比较，每对都有积极和消极的期望。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Distinguishing acupuncture from placebo acupuncture has been a methodological challenge. We propose to use a quantitative brain imaging method to investigate the mechanism of acupuncture analgesia, placebo analgesia and their interrelationship. A well tested method to induce high and low expectation will be combined with acupuncture analgesia and sham acupuncture analgesia to create a 2 X 2 comparison of verum acupuncture and sham acupuncture each paired with positive and negative expectancies.