Immune Function and Biodefense in Immunocrompromised Populations

该计划将开发新的方法，用于保护或治疗处于生物恐怖威胁风险中的免疫缺陷个体。该研究计划包括确定导致这些人群对感染的易感性增加或疫苗有效性降低的生物学机制，以及测试旨在提高安全性或有效性的治疗方法的临床研究。这项研究将导致在免疫功能低下的人群中预防传染病。

This program will develop novel methods for protecting or treating immunocrompromised individuals at risk from bioterror threats. The research program covers the identification of biological mechanisms responsible for increased susceptibility to infection or decreased effectiveness of vaccines in these populations, as well as clinical research to test treatments designed to increase safety or efficacy. This research will lead to the prevention of infectious disease in immunocompromised populations.