HISTOLOGY CORE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 NVCI组织学核心的目标是向所有研究人员提供培养细胞以及动物和人体组织的形态学，免疫组织化学和原位分析所需的专业知识，设施，技术和技术支持。 核心设施主管是美国病理学委员会认证的病理学家和分子实验科学家，他们受过高水平的培训和专业知识。 他们为研究人员提供咨询，解释标本中的组织病理学变化，并确定制备人类和实验动物细胞和组织用于形态学研究的最佳程序。 所提供的服务包括：1）常规石蜡包埋组织学，包括特殊组织学染色，2）冷冻和石蜡包埋组织的免疫组织化学，以及mRNA的原位分析，3）组织微阵列分析，和4）病理学/形态学解释。 这一核心将通过提供单个实验室无法提供的服务提高研究的生产力，并使研究人员能够专注于自己的项目，而无需制定自己的组织学、免疫组织化学和原位杂交方案。 此外，它还为调查人员提供一致的高质量结果。 INBRE奖支持一名半职技术人员和购买小型设备。 作为这种支持的交换，所有内华达州的研究人员都可以以折扣价获得组织学核心服务。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of the Histology Core at NVCI is to make available to all investigators the expertise, facilities, techniques and technical support required for morphological, immunohistochemical and in situ analysis of cultured cells as well as animal and human tissues. The core facility supervisors are an American Board of Pathology certified pathologist and a molecular experimental scientist with high levels of training and expertise. They provide consultation to investigators on interpretation of histopathological changes in specimens and identifying optimal procedures for preparing cells and tissue of humans and experimental animals for morphologic studies. The services provided include: 1) routine paraffin-embedded histology including special histological stains, 2) immunohistochemistry on frozen and paraffin embedded tissues, and in situ analysis of mRNA, 3) tissue micro-array analysis, and 4) pathology/morphology interpretation. This core will enhance the productivity of research by providing services not available in individual laboratories and allowing investigators to concentrate on their own projects without the need to develop their own histology, immunohistochemistry and in-situ hybridization protocols. In addition, it also provides consistent, high-quality results to investigators. The INBRE award supports a half-time technician and the purchase of small equipment. In exchange for this support, all Nevada researchers are provided access to Histology core services at a discounted rate.