HISTOLOGY CORE

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。NVCI组织学核心的目标是为所有研究人员提供形态学、免疫组织化学研究和培养细胞、动物和人体组织原位分析所需的专业知识、设施、技术和技术支持。核心导师是美国病理学委员会认证的病理学家和具有高水平培训和专业知识的分子实验科学家。他们为研究人员提供组织病理学变化的解释和确定用于形态学研究的实验动物和人类细胞和组织的最佳制备程序的咨询。提供的服务包括：1)常规石蜡包埋组织学，包括特殊的组织染色，2)冷冻组织和石蜡包埋组织的免疫组织化学，mRNA的原位分析，3)组织微阵列分析，4)病理/形态学解释。通过提供单个实验室无法提供的服务，该核心将提高研究效率，并允许研究人员专注于自己的项目，而无需开发自己的组织学和免疫组织化学以及原位杂交。此外，它还为研究者提供一致的、高质量的结果。INBRE奖支持一名兼职技术员和购买小型设备。作为对这种支持的交换，所有内华达州的研究人员都能以折扣价获得组织学服务。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of the Histology Core at NVCI is to make available to all investigators the expertise, facilities, techniques and technical support required for morphological, immunohistochemical studies and in situ analysis of culture cells, animal and human tissues. The core supervisors are an American Board of Pathology certified pathologist and a molecular experimental scientist with high levels of training and expertise. They provide consultation to investigators on interpretation of histopathological changes and identifying optimal procedure for preparing cells and tissues of experimental animal and human for morphologic studies. Provided services include: 1) routine paraffin embedded histology including special histological stains, 2) immunohistochemistry on frozen and paraffin embedded tissues, and in situ analysis of mRNA, 3) tissue micro-array analysis, and 4) pathology/morphology interpretation. This core will enhance the productivity of research by providing services not available in individual laboratories and allowing investigators to concentrate on their own projects without the need to develop their own histology and immunohistochemistry and in situ hybridization. In addition, it also provides consistent, high-quality results to investigators. The INBRE award support a half-time technician and the purchase of small equipment. In exchange for that support, all Nevada researchers are provided with histology services at a discounted rate.