A Novel Handheld Three-Dimensional Camera for Wound Healing Monitoring

描述(由申请人提供)：我们提出这个第二阶段SBIR计划，以进一步利用我们第一阶段的非常有希望的结果，开发一种新型的手持三维(3D)相机，能够对伤口的大小、形状、体积、颜色和愈合状态进行客观、定量和真实的3D测量。精确的伤口愈合测量使临床医生能够评估、记录、改进和个性化为每个伤口患者提供的治疗计划。在目前的伤口护理实践中，临床医生经常通过肉眼检查伤口来评估愈合状态。这不是一种最佳做法，因为人类的视觉缺乏精确度和一致性，而且很难量化缓慢或微妙的变化。因此，一种量化肤色和几何形状变化的仪器在帮助临床医生评估愈合状态和判断充血、血肿、局部炎症、继发感染和组织坏死的影响方面将特别有用。我们在SBIR计划下开发的手持式3D摄像机将证明自己在监控伤口护理方面比传统方法具有几个独特的优势，包括： 非接触式测量：无污染伤口部位或干扰恢复组织的风险。快速且易于使用：在几分之一秒内获取一张图像，并实时自动将多个3D图像合并为完整的伤口3D模型；适用于医院和家庭护理/远程医疗应用。高精度：亚毫米精度，最佳景深，确保准确捕捉暗示愈合的变化，并尽量减少伪影。定量测量：2D颜色和3D形状都提供伤口参数的定量数字测量，如面积大小、体积、长度、深度、表面粗糙度及其轮廓。手持设备：它不仅是一种方便的便携式仪器，还提供了一种独特的能力，可以测量四肢周围延伸的伤口，这些伤口不能从单一位置完全看到。 大众商业市场的合理成本：拟议的手持式3D摄像机设计导致生产成本低廉。我们将这种系统投入批量生产的目标价格定在1,000美元以下。拟议的手持3D相机产品如果成功，预计将在临床、家庭护理和远程医疗应用中具有巨大的市场潜力。

DESCRIPTION (provided by applicant): We propose this Phase II SBIR program to further capitalize on the very promising results from our Phase I effort to develop a novel, handheld three-dimensional (3D) camera able to perform objective, quantitative, and true 3D measurements of the size, shape, volume, color, and healing status of wounds. Accurate measurement of wound healing enables clinicians to assess, document, improve, and individualize the treatment plan given to each wound patient. In current wound care practices, clinicians often visually inspect the wound to evaluate the healing status. This is not an optimal practice because human vision lacks precision and consistency, and quantifying slow or subtle changes is very difficult. As a result, an instrument that quantifies both skin color and geometric shape variations would be particularly useful in helping clinicians assess healing status and judge the effect of hyperemia, hematoma, local inflammation, secondary infection, and tissue necrosis. Our handheld 3D camera developed under this SBIR program will prove itself to have several unique advantages over traditional methods for monitoring wound care, to include: Non-contact measurement: No risk of contaminating the wound site or disturbing the recovering tissue. Fast and easy to use: Acquires a single image in a fraction of a second and automatically merges multiple 3D images into a complete 3D model of the wound in real time; suitable for both hospital and homecare/telemedicine applications. High Accuracy: Sub-millimeter accuracy with optimal depth of field to ensure that changes suggestive of healing are captured precisely and with minimal artifact. Quantitative measurements: Both 2D color and 3D shape provide quantitative digital measurements of wound parameters such as area size, volume, length, depth, surface roughness, and its profile. Handheld device: Not only is it a handy portable instrument, it also provides a unique ability to measure wounds that extend around limbs and that are not fully visible from a single position. Reasonable cost for mass commercial market: The proposed handheld 3D camera design leads to inexpensive production. Our targeted price for such a system in mass production is under $1,000. The proposed handheld 3D camera product, if successful, is expected to have tremendous market potential in clinical, homecare, and telemedicine applications.