D6ZIPGC BRANCH-POINT DOMAIN

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 我们正在研究金属离子对第二组内含子结构域6 RNA分支点的影响。为了进一步了解分支点周围的特定构象变化，我们计划与麦迪逊的Samuel Butcher教授的实验室合作，用PF1噬菌体排列的RNA测量剩余的偶极耦合。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are investigating the impact of metal ions on the branchpoint of a group II intron domain 6 RNA. To achieve further insights into specific conformational changes around the branch-point we are planning on measuring residual dipolar couplings with Pf1 phage aligned RNA in cooperation with the lab of Prof. Samuel Butcher at Madison.