课题基金 / 基金详情

MEMBRANE-BINDING OF THE ENTH DOMAIN

MEMBRANE-BINDING OF THE ENTH DOMAIN
ENTH 结构域的膜结合
批准号：
7600952
负责人：
WONHWA CHO
金额：
$1.34万
依托单位：
UNIVERSITY OF CALIFORNIA-IRVINE
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
已结题
起止时间：
2007-08-01 至 2008-07-31
来源：
https://reporter.nih.gov/project-details/7600952
关键词：
BindingComputer Retrieval of Information on Scientific Projects DatabaseFundingGrantInstitutionMeasuresMembraneProtein BindingResearchResearch PersonnelResourcesSourceSurfaceUnited States National Institutes of Health

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 ENTH结构域是结合PI（4，5）P2并诱导膜变形的蛋白质。为了理解其膜变形活性的机制，我们将通过PCH分析测量ENTH结构域在膜表面上的聚集。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The ENTH domain is a protein that binds PI(4,5)P2 and induces membrane deformation. To understand the mechanism of its membrane-deforming activity, we will measure the aggregation of the ENTH domain on the membrane surface by PCH analysis.
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