DYNAMIC PULMONARY IMAGING USING DYNAMIC CONTRAST-ENHANCED MR IMAGING

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在啮齿动物的肺部进行真正的动态成像，使用超极化气体、氦和氙气进行螺旋成像。 第一个目标是了解呼吸周期的动力学，并只执行质子扫描，以优化螺旋序列的成像和定时参数。下一个目标是扩展这些扫描，以展示执行动态惠普气体研究的能力。 这些研究将影响该中心今后的工作。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Perform true dynamic imaging in rodent lungs using spiral imaging using hyperpolarized gases, Helium and Xenon. The first goal is to understand the dynamics of the respiratory cycle, and perform only proton scans to optimize the imaging and timing parameters of the spiral sequence. The next goal is to extend these scans to demonstrate the capability of performing dynamic HP gas studies. These studies will impact future work in the Center.