DATA COLLECTION OF SEVERAL GENOME MAINTENANCE PROTEINS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 我们有几个项目已经形成了很小或很小的晶体 对我们的本土光源产生微弱的衍射光。其中包括几种不同的蛋白质(或结构域 它们)或对DNA复制、重组、 并进行修复。我们正在寻找BioCARS固定波长光束线上的时间来评估 其中几种的衍射特性及采集高分辨率(~2埃) 另外两个的数据集。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have several projects that have resulted in formation of crystals that are small or that diffract weakly on our home source. These include several different proteins (or domains thereof) or protein/ligand complexes that are important for DNA replication, recombination, and repair. We are seeking time on the BioCARS fixed wavelength beamline to assess diffraction charateristics of several of these and to collect high resolution (~2 angstroms) data sets of two others.