TULANE COBRE: GENETIC POLYMORPHISMS IN EPOXYGENASE PATHWAY IN HYPERTENSION

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在项目4中，德雷斯巴赫测试了一种假设，即细胞色素花生四烯酸途径和缓激肽受体中常见的基因多态单独或联合导致20-HETE和EETs水平改变，这在人类对盐敏感和耐盐的高血压中发挥机制作用。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. For Project 4, Dreisbach tests the hypothesis that common genetic polymorphisms in both CYP (cytochrome) arachidonate pathways and the bradykinin receptors individually or in combination lead to altered levels of 20-HETE and EETs that play a mechanistic role in salt-sensitive and salt-resistant hypertension in humans.