ADMINISTRATIVE CORE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者的研究机构。 夏威夷大学临床研究中心（UH CRC）成立于1995年，由太平洋生物医学研究中心（PBRC）和约翰A。夏威夷大学（UH）伯恩斯医学院（JABSOM）和卡皮奥拉尼妇女和儿童医疗中心（KMCWC）。 自该计划开始以来，UH CRC在KMCWC开设了一个门诊研究诊所，该诊所一直是其临床活动的主要基地。 在目前的资助周期内，UH CRC已扩大到包括女王医疗中心（QMC）的磁共振（MR）核心实验室，目前正在计划在QMC开发一个新的门诊研究诊所。 该方案还扩大到包括在Leahi医院的夏威夷艾滋病临床研究方案的艾滋病毒研究核心，并正在实施在夏威夷凯泽永久健康研究中心开发生物营养素研究核心的计划。 最后，通过建立临床研究开发项目（CRDP）机制，UH CRC计划基金已承诺支持多达三个有前途的临床研究人员在他们的进展独立的研究赠款。 这与UH的整体生物医学研究议程一致，加强了其竞争NIH机构临床转化科学奖的地位。 在与竞争性续约申请中描述的优先事项一致的情况下，UH CRC继续专注于实现其主要目标  为临床研究提供基础设施支持，旨在改善夏威夷多样化人口的健康和福祉。 该计划的具体目标已被修改，以反映NIH对转化研究的重视，并总结如下： 目标1： 继续提供必要的物质和智力基础设施，以支持在呃安全和文化上适当的临床研究。 目标二： 培养和发展训练有素和富有成效的临床研究人员。 目标3： 建立和完善早期人类发展，生物营养，艾滋病毒和癌症的临床卓越和专业知识，特别强调与夏威夷州人口临床相关的问题。 目标4： 继续合作开展基于社区的参与性研究，并通过拟议的临床转化科学奖（CTSA）扩大研究合作。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The University of Hawaii Clinical Research Center (UH CRC) was established in 1995 through a collaboration between the Pacific Biomedical Research Center (PBRC) and John A. Burns School of Medicine (JABSOM) of the University of Hawaii (UH), and the Kapiolani Medical Center for Women and Children (KMCWC). Since inception of the program, the UH CRC has operated an outpatient research clinic at KMCWC, which has served as its primary base of clinical activity. During the current funding cycle, the UH CRC has been expanded to include a Magnetic Resonance (MR) Core Lab at The Queen's Medical Center (QMC), with plans for development of a new outpatient research clinic at QMC currently underway. The program has also expanded to include a HIV research core with the Hawaii AIDS Clinical Research Program (HACRP) at Leahi Hospital, and is pursuing plans to develop a Bionutrition research core at the Kaiser Permanente Center for Health Research Hawaii (CHRH). Lastly, through establishment of the Clinical Research Development Project (CRDP) mechanism, UH CRC program funds have been committed to support up to three promising clinical investigators in their progression towards independent research grants. This is done in congruence with the overall biomedical research agenda of UH, strengthening its position to compete for a NIH institutional Clinical Translational Science Award. In congruence with the priorities delineated in its competitive renewal application, the UH CRC has continued to focus upon achievement of its primary objective  to provide infrastructure support for clinical research designed to improve the health and well-being of Hawaii's diverse population. The specific aims for the program have been modified to reflect the NIH's emphasis on translational research, and are summarized as follows: Aim 1: To continue to provide the necessary physical and intellectual infrastructure to support safe and culturally appropriate clinical research at UH. Aim 2: To cultivate and develop well-trained and productive clinical research faculty. Aim 3: To build and refine clinical excellence and expertise in Early Human Development, Bionutrition, HIV and Cancer, with particular emphasis on issues of clinical relevance to the populations of the State of Hawaii. Aim 4: To continue to partner on community-based participatory research and to expand research collaborations through the proposed Clinical Translational Science Award (CTSA).