Small Imaging Core

小动物成像(WUSAIR)核心 华盛顿大学小动物影像资源(WUSAIR)是五个原始的小动物之一 动物影像研究计划(SAIRP)中心成立于1999年，并于2004年进行了竞争性续签。 WUSAIR提供最先进的设施和基础设施，用于MRI、PET、CT、SPECT和光学成像 小鼠、大鼠和其他小型实验动物。位于华盛顿大学医疗中心 在WUSAIR中心，WUSAIR结合了其他几个机构所没有的工具和智力能力。WUSAIR 服务于广泛的癌症科学家社区，他们是MRI、CT、PET或光学技术的非专家，他们拥有 迫切需要对小型实验动物模型系统进行定量图像分析。一个特别的焦点是 在小鼠和大鼠的癌症模型上。WUSAIR还在以下前沿提供研究和开发 成像技术，努力为其社区提供最强大的新成像策略 用户。 WUSAIR成像模式得到以下操作仪器的支持：microPET， MicroCT、NanSpect、小动物4.7T和11.74T MRI、光学吸收、荧光、漫反射光学 断层扫描(DOT)和体内生物发光成像，以及光学显微镜，通过商业 和定制的系统。有关插装的完整列表，请参阅参考资料。辅助服务和 WUSAIR的能力包括为开发和设计新的 硬件和成像方法；为本地和远程数据访问、分析、可视化提供信息学支持 和档案；新造影剂开发；实验计划和数据的生物统计学咨询 分析；以及外科手术、导管放置和维护的动物程序辅助，以及 成像实验期间的生理状态监测。 WUSAIR将为NTR提供全面的小动物成像资源，用于开发 探头和临床前评估以及成像方法的验证。WUSAIR还提供了以下潜力 自然资源保护网络的其他成员利用综合的小动物成像资源。这将是 对于缺乏WUSAIR所代表的众多成像方式中的一种的机构来说，这是特别有益的。 重要的是，WUSAIR将有助于快速有效地促进新项目，因此与 非现场调查人员。

Small Animal Imaging (WUSAIR) Core The Washington University Small Animal Imaging Resource (WUSAIR) is one of the five original Small Animal Imaging Research Program (SAIRP) centers funded in 1999 and was competitively renewed in 2004. WUSAIR provides state-of-the-art facilities and infrastructure for MRI, PET, CT, SPECT and optical imaging of mice, rats and other small laboratory animals. Located in the heart of the Washington University Medical Center, WUSAIR combines instrumental and intellectual capabilities found at few other institutions. WUSAIR serves a broad community of cancer scientists, non-experts in MRI, CT, PET or optical technology, who have a pressing need for quantitative image analysis of small laboratory animal model systems. A particular focus is on mouse and rat models of cancer. WUSAIR also provides research and development at the frontier of imaging technology in an effort to make the most powerful new imaging strategies available to its community of users. WUSAIR imaging modalities are supported by the following operational instrumentation: microPET, microCT, nanoSpect, small animal 4.7 T and 11.74 T MRI, optical absorption, fluorescence, diffuse optical tomography (DOT) and bioluminescence in vivo imaging, and optical microscopy, through both commercial and custom built systems. See resources for a complete listing of instrumentation. The ancillary services and capabilities within WUSAIR include physics and engineering support for the development and design of new hardware and imaging methods; informatics support for local and remote data access, analysis, visualization and archival; new contrast-agent development; biostatistics consultation for experiment planning and data analysis; and animal procedure assistance for surgical procedures, catheter placement and maintenance, and monitoring of physiologic status during imaging experiments. WUSAIR will provide the NTR with comprehensive small-animal imaging resources for development of probes and pre-clinical evaluations and validation of imaging methods. WUSAIR also provides the potential for other members of the NTR-Networks to utilize comprehensive small-animal imaging resources. This will be of particular benefit to institutions lacking in one of the many imaging modalities represented by WUSAIR. Importantly, WUSAIR will help to facilitate new projects quickly and efficiently and thus is compatible with offsite investigators.