Integrative Training in Biomedical Systems

描述（由申请人提供）：这是一份经过广泛修订的培训计划拨款申请，旨在支持3名学生参加以“人类疾病生物学”为主题的综合生物医学科学研究生课程（IBGP）的前两年。该计划的学生将根据学术成就和对人类疾病机制的跨学科研究的兴趣，从IBGP第一年的学生中选择。在这两年里，学生们将学习严格的、基础广泛的核心课程，包括讲座、研讨会、小组讨论和实验室轮换。在第一年结束时，所有学生都选择一个论文顾问和咨询委员会，他们指导他们进行跨学科研究项目，并建议他们选择高级课程和研讨会。这将有助于他们整合与他们跨学科论文研究有关的材料，这些研究涉及人类疾病机制的复杂相互作用。第一年之后，该项目的学生每年至少有一个季度的时间参加综合生物医学科学高级研讨会。为了帮助学生在完成核心课程后选择课程和研讨会，我们设计了9个传统研究学科的建议课程，如果遵循这些课程，他们的最终成绩单将指定该领域为研究生专业。本课程的许多学生可能希望在多个领域（称为研究重点领域）获得研究生专业。这个培训项目在这9个研究重点领域都有优秀的研究生教师，他们可以担任论文顾问和咨询委员会成员，其中一名教师担任该领域的教师联络人。这名教师可以与学生讨论他所代表的研究重点领域的不同方面。候选资格考试将在第三年初进行。它将包括：(1)由学生撰写的关于拟议的跨学科论文研究项目的资助申请；(2)口试，以测试学生对拟议的跨学科研究项目相关的信息和概念的整合。在此之后，大部分学生的努力将花在研究上，最终将在论文中进行口头辩护；毕业时间不超过5年。我们相信，课程，教师和资源支持这一培训计划将吸引优秀的学生谁将成为杰出的，富有成效的科学家在综合生物医学研究。

DESCRIPTION (provided by applicant): This is an extensively revised grant application for a training program to support 3 students in each of the first 2 years of an Integrated Biomedical Science Graduate Program (IBGP) having the theme "The Biology of Human Disease." Students for this program will be selected from the pool of students in the first year of the IBGP on the basis of academic achievements and an interest in interdisciplinary studies on mechanisms of human disease. During these 2 years students take a rigorous, broadly based core curriculum consisting of lectures, seminars, group discussions and laboratory rotations. At the end of year 1 all students choose a dissertation advisor and advisory committee who guide them in an interdisciplinary research project, and advise them on the selection of advanced courses and seminars. These will help them to integrate material related to their cross-disciplinary dissertation research on complex interactions underlying the mechanisms responsible for human disease(s). After the first year, students in the program will take an advanced seminar in integrated biomedical science for at least one quarter each year. To assist students in the choice of courses and seminars after completion of the core courses, we have designed suggested curricula in 9 traditional research disciplines, which if followed will result in their final transcripts designating this area as a graduate specialization. Many students in this program will probably want to obtain graduate specialization in more than one area (referred to as areas of research emphasis). This training program has excellent graduate faculty in each of these 9 areas of research emphasis who can serve as dissertation advisors and advisory committee members, and one of these faculty members serves as a faculty liaison for an area. This faculty member is available to discuss with students different aspects of the area of research emphasis he represents. The candidacy exam will be taken early in the third year. It will consist of: (1) A grant application written by the student on the proposed interdisciplinary dissertation research project; (2) An oral examination to test the student's integration of information and concepts related to the proposed cross-disciplinary research project. Subsequent to this most of the students' efforts will be spent on research that will culminate in a dissertation that will be defended orally; the time to graduation should be no more than 5 years. We believe that the curriculum, faculty and resources supporting this training program will attract outstanding students who will become distinguished, productive scientists in integrative biomedical research.