Wireless Subdural Electrode Array

描述（由申请人提供）：在本翻译SBIR项目中，我们将开发一种完全植入式无线硬膜下电极网格，用于短期皮层EEG监测（少于30天）。该设备将基于新的制造工艺，该工艺将允许以低成本和与现有有线电网竞争的价格合成具有集成电子器件的无线植入物。这种完全植入的硬膜下网格的可用性将大大降低与皮层EEG监测程序相关的住院费用和感染率。公共卫生相关性：手术干预是治疗癫痫的一种昂贵、时间密集、未充分利用的技术，只有不到5%的潜在辅助患者群体以这种方式接受治疗。完全植入的无线设备将降低感染率，并需要不那么严格的护理环境，而更便宜的设备和护理方法将有助于降低医疗保健成本，增加潜在的治疗人群。这将使临床医生能够使用更便宜的治疗方案，并将癫痫监测程序从昂贵的神经科重症监护病房中移出。

DESCRIPTION (provided by applicant): In this translational SBIR program, we will develop a totally implantable, wireless, subdural electrode grid for short-term cortical EEG monitoring (less than 30 days). This device will be based upon novel manufacturing processes that will allow synthesis of the wireless implants with integrated electronics at low cost and prices that are competitive with existing wired grids. The availability of this fully implanted subdural grid will substantially reduce hospitalization costs and infection rates associated with cortical EEG monitoring procedures. PUBILC HEALTH RELEVANCE: Surgical intervention is an expensive, time intensive, underutilized technique to treat epilepsy, with less than 5% of the potentially aided patient population being treated in this way. A fully implanted wireless device will reduce infection rates and require a less stringent care environment, while cheaper devices and care methods will help to reduce health care costs and increase potential treatment populations. This will enable clinicians to use less expensive treatment options and to move epilepsy monitoring procedures out of expensive Neurology Intensive Care Units.