Administrative Core

管理核心包括生物统计学、临床试验管理、护理和药剂学。这个核心 在所有项目中发挥不可或缺的作用，提供一个密切互动的生物统计小组，该小组被整合到 在项目1-3中为所有临床试验提供每个项目、护理、数据管理和药房支持。 生物统计小组在这一项目中的作用是帮助设计、实施和分析 临床试验和临床前试验。管理核心通过以下方式支持数据管理 MSKCC临床研究室。该办公室负责患者登记、数据管理 支持、质量保证/控制、监管事务和与FDA的接口、方案监督和 协助方案审查。该项目的数据经理每周都会参加会议并参与 病人接受治疗的诊所会议。免疫学研究护士是经验丰富的护士， 提供包括单抗和疫苗在内的治疗方法，执行患者监测，并记录毒性数据。终于 研究药剂师处理和储存疫苗，并为治疗做准备，维护 适当的记录。

The Administrative Core includes biostatistics, clinical trials management, nursing, and pharmacy. This core plays an integral part in all projects, providing a closely interactive biostatistics group that is integrated into each Project, nursing, data management and pharmacy support for all clinical trials throughout Projects 1-3. The role of the biostatistics group for this project is to contribute to the design, conduct and analysis of the clinical trials, and preclinical experiments. The Administrative Core supports data management through the Office of Clinical Research at MSKCC. This office is responsible for patient registration, data management support, quality assurance/control, regulatory affairs and interfacing with the FDA, protocol oversight, and assisting protocol review. The data managers on this program attend meetings weekly and participate in clinic sessions where patients are treated. The Immunology Research Nurses are experienced nurses who deliver therapies including mAb and vaccines, perform patient monitoring, and record data of toxicity. Finally the research pharmacist handles and stores vaccines, and prepares them for treatment, with maintenance of appropriate records.