Administration Core

行政核心的作用 行政核心既提供行政监督，也提供知识监督和指导 财务会计制度。Bette Sheehan女士和Randy Martinson先生提供 和财务专业知识。 女士贝蒂·希恩负责监督该项目的社区行政服务。她组织 由该计划发起和维持的每周学生和博士后研讨会。她负责管理 并促进每个项目的履行不断增加的文件需要进行我们的研究 包括人类受试者安全批准、脊椎动物使用批准、生物安全批准，以及 化学安全认证。她组织项目负责人的会议，将他们的手稿存档， 监督学生委员会会议正是这些努力为萨格登博士提供了一种手段， 首席研究员随时了解项目成员开展的最新研究。他 与项目负责人每周举行一次会议，并组织每周工作人员联席会议 由希恩女士，提供了第二种手段博士。希恩女士 还将组织我们的科学顾问委员会成员的访问。我们建议把成员 个别和有时一起到麦迪逊，以促进我们的癌症研究卓越。 先生兰迪·马丁森负责监督这项计划项目赠款的财务会计。他提供 每个项目负责人不断报告他们的预算和支出，并告知萨格登博士的潜力， 在困难发生之前。他在为我们的供应品争取最有竞争力的价格方面起了重要作用。 使用.例如，他组织了该计划与限制性内切酶供应商的合同 这不仅为我们提供了尽可能低的价格，而且还可以立即获得它们， 存放在麦卡德尔马丁森先生还指导项目负责人准确预测未来的预算 并在满足联邦和州政府，大学和医疗的会计要求 管理该方案资金的学校。 这个核心的两个方面提供知识监督和指导。萨格登医生通常会 每周多次与项目负责人讨论科学和人员问题。他是一名成员， 大部分研究生的论文委员会开展本计划的研究。 他阅读了许多描述该计划研究的初稿，并建议 酌情修订。同样清楚的是，所有的项目负责人都是他们领域的专家。 领域，以便萨格登博士已经并将继续对该计划作出的重大贡献是促进 他们之间的合作。例如，保罗·阿尔奎斯特博士和保罗· Lambert和他的目标是确定可能由以下原因引起的其他人类癌症： 人肿瘤病毒。 第二个方面，该核心将为其研究提供智力监督和指导 是通过它的科学顾问委员会。四名研究领域与项目领域重叠的专家将前来， 每年对该计划的科学性进行批判性审查。DiMaio博士是乳头状瘤病毒方面的专家， 对病毒学的理解。鲁尼博士是爱泼斯坦-巴尔病毒的专家， 将研究成果转化为治疗EBV相关癌症的有效疗法。他们不是 被要求批评拨款申请，而不是访问和批判性地审查正在进行的研究。的 项目负责人和主要研究人员将介绍他们目前和拟议的研究，供大家讨论。的 项目成员希望这些专家同事能够了解他们的科学，并帮助他们 合作蓬勃发展。萨格登博士将在每次访问结束时与顾问私下会面， 关于他促成项目成功的敏感建议

Role of the Administrative Core The Administrative Core provides both administrative as well as intellectual oversight and guidance and financial accounting for the Program. Ms. Bette Sheehan and Mr. Randy Martinson provide the administrative and financial expertise required for this Core. Ms. Bette Sheehan oversees the communal administrative services for this program. She organizes the weekly student and postdoctoral seminars initiated and maintained by this Program. She administers and facilitates each project's fulfilling the ever-increasing documentation required to carry out our research including human subjects safety approval, vertebrate animal use approval, biological safety approval, and chemical safety approval. She organizes meetings of the project leaders, archiving their manuscripts, and overseeing their students' committee meetings. It is these efforts that provide one means for Dr. Sugden as the principal investigator to stay abreast of the current research carried out by Program members. His weekly meetings with the Project leaders and their combined weekly staff meeting, which is also organized by Ms. Sheehan, provides a second means for Dr. Sugden to affect this Program's research. Ms. Sheehan will also organize the visits of our scientific advisory board members. We propose to bring the members individually and sometimes together to Madison to foster excellence in our cancer research. Mr. Randy Martinson oversees the financial accounting for this Program-Project grant. He provides each project leader ongoing reports of their budgets and expenditures and informs Dr. Sugden of potential difficulties before they occur. He is instrumental in obtaining the most competitive prices for the supplies we use. For example, he organized the Program's initiating a contract with a vendor of restriction endonucleases which provides us not only the lowest possible prices but also immediate access to them, their being stored in McArdle. Mr. Martinson also guides project leaders in their projecting accurately future budgets and in meeting the accounting demands of federal and state governments, the University, and the Medical School through which the Program's funds are administered. Intellectual oversight and guidance is provided by two facets of this core. Dr. Sugden usually meets with project leaders multiple times per week to discuss science and personnel. He is a member on the dissertation committees of the majority of the graduate students carrying out the research of this program. He reads many of the manuscripts describing this program's research in their initial draft form and suggests revisions where appropriate. It is also clear that all of the project leaders are established experts in their fields so that a major contribution Dr. Sugden has and will continue to make to this program is to foster collaboration between them. For example, it is in part through his efforts that Drs. Paul Ahlquist and Paul Lambert and he have united in their goal to identify additional human cancers that may be caused by human tumor viruses. The second facet by which this core will provide intellectual oversight and guidance for its research is through its scientific advisory board. Four experts whose research overlaps project areas shall come and review the program's science critically each year. Dr. DiMaio is an expert in papillomaviruses with a breadth of understanding of virology in general. Dr. Rooney is an expert in Epstein-Barr virus with experience in developing research findings into effective therapies for treating EBV-associated cancers. They are not being asked to critique the grant application but rather to visit and critically review ongoing research. The project leaders and key researchers will present their current and proposed research for all to discuss. The program members want these expert colleagues to grow to know their science and .to help their collaborations flourish. Dr. Sugden will meet privately with the advisors at the end of each visit to seek any sensitive suggestions about his fostering the success of the program.