Developmental Research Program

认识到发展研究基金是SPORE的一个组成部分，我们承诺每 这些年的努力。此外，每年50，000美元的配套资金承诺用于该计划， 密歇根大学医学院。这占了UMCC预算的很大一部分 头部和颈部孢子，并反映了该计划的持续承诺，以发展 头颈癌的创新转化研究。发展研究的重点 该计划旨在为调查人员提供生成数据的能力，这些数据将成为 R 01同等提案的资助申请。来自头颈部领域以外的调查人员 鼓励癌症申请通过校园范围内的公告，以及通过个人 与SPORE调查人员的互动。一个逐步的提案征求和审查过程已经完成， 利用NIH型PHS 398格式应用程序开发，该应用程序已被简化以快速周转 该委员会注意到，研究计划的初步数据可能很少。 调查人员可申请为期一年或两年的50 000美元支助。以来 2002年，我们资助了18个发展项目，总投资额为79万美元; 导致超过260万美元（直接费用）的后续赠款，13份手稿和4份摘要。博士 格雷戈里·沃尔夫和托马斯凯里博士担任发展研究计划的主任。两者都是 领导人在头部和颈部癌症，并担任机构领导职务。与高级 咨询理事会，他们善于选择最高质量的建议，以资助和提供 必要的指导和支持，以保证该计划的成功。

Recognizing that developmental research funds are an integral part of the SPORE, we commit $75,000 per year to these endeavors. In addition, matching funds of $50,000/year are committed to this program from the University of Michigan Medical School. This represents a significant percent of the budget of the UMCC Head and Neck SPORE and reflects the continued commitment of this program to the development of innovative translational research in head and neck cancer. The focus of the Developmental Research Program is to provide investigators the ability to generate data that will become the preliminary data for an R01 grant application of an equivalent proposal. Investigators from outside the field of head and neck cancer are encouraged to apply through campus-wide announcements as well as through personal interactions with SPORE investigators. A stepwise proposal solicitation and review process has been developed utilizing NIH-type PHS 398 format applications that have been streamlined for rapid turn around of research proposals and which recognizes that these projects may have little preliminary data. Investigators may apply for support in the amount of $50,000 for a one- or two-year funding period. Since 2002 we have funded 18 developmental projects, representing a total investment of $790,000; This has resulted in over $2.6 million (direct costs) in subsequent grants, 13 manuscripts, and 4 abstracts. Dr. Gregory Wolf and Dr. Thomas Carey serve as Directors for the Developmental Research Program. Both are leaders in head and neck cancer, and hold institutional leadership positions. Together with the Senior Advisory Council, they are adept at selecting the highest quality proposals for funding and providing the necessary mentorship and support to guarantee success with this program.