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中文摘要
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描述(由申请人提供):我们醒着的大部分时间都是久坐不动的(例如,倾斜、静坐),花在这些行为上的时间与能量消耗减少、增加体重增加的风险和慢性病独立相关。对久坐行为(SB)感兴趣的研究人员和医疗保健提供者的努力将得到极大的加强,因为一种有效且易于管理的基于人群的研究工具可以从背景、背景、目的、类型和数量方面评估SBS。这样的工具将更全面地揭示SBS对健康的影响,并将允许测量对干预措施做出反应的行为变化。我们的总体目标是开发一种长度可控的工具,提供人群中主要SBS的全面概况,并对这些行为产生不同的衡量标准。我们建议在两个人群(青少年和成人)中进行一项研究计划,以确定镇静对健康的不利影响。首先,我们将使用现有的国家数据来源和从头开始的描述性研究(N=200)的信息,从流行率和持续时间方面仔细描述最重要的SBS。我们将利用这些描述性研究来同时开发和提炼三份SB问卷:两份特定年龄的工具(青少年、成年人)和一种可能适用于两个年龄组的共同测量方法。我们将使用描述性研究、认知测试和专家评审的结果来确定通用措施的可行性。如果可行,我们将在研究的第二部分对其进行评估。如果没有,我们将评估特定年龄的工具。其次,我们将采用自我报告和客观测量相结合的方法,对新的青少年问卷(S)进行信度和效度研究。除了通过因子分析评估SBQ的心理测量学特性外,我们还将进行探索性分析,以确定可以作为该工具的缩写的条目子集(S)。第三,我们将通过网络免费发布新的SBQ及其评分算法。我们预计,在本研究计划中开发的工具将促进试图描述SBS发生地点和原因的研究,检查SBS对健康的不利影响的病因学研究,以及寻求量化这些行为在干预或健康促进计划中的变化的临床和干预研究。与公共健康相关:我们醒着的大部分时间都是久坐不动的,花在这些行为上的时间与肥胖和慢性病有关。对久坐行为(SB)感兴趣的研究人员和医疗保健提供者的努力将大大加强,因为存在一种有效且易于管理的工具来测量SB。我们寻求开发一份长度可控的问卷,全面评估人口中的主要SBS。 纳入妇女计划:一半的目标和计划招生包括妇女。 纳入少数群体计划:有针对性和有计划的入学包括与地理位置一致的少数群体代表。 纳入儿童计划:这项研究将招募同等数量的儿童(12-17岁)作为成年人。
英文摘要
DESCRIPTION (provided by applicant): We are sedentary for the majority of our waking hours (e.g., reclining, sitting still) and time spent in these behaviors have been independently associated with reduced energy expenditure, increased risk for weight gain, and chronic disease. The efforts of researchers and health care providers interested in sedentary behavior (SB) would be greatly enhanced by a valid and easy- to-administer instrument for population-based studies that can assess SBs in terms of their context, setting, purpose, type, and amount. Such an instrument would reveal more fully the impact of SBs on health, and would allow a measurement of changes in behaviors in response to interventions. Our overall goal is to develop an instrument of manageable length that provides a comprehensive profile of major SBs in the population, and that produces a heterogeneous measure of these behaviors. We propose a research program to be conducted in two populations (adolescents and adults) at risk for the adverse health consequences of sedentarism. First, we will describe carefully the most important SBs in terms of the prevalence and duration using available national data sources and information from a de novo descriptive study (N=200). We will use these descriptive studies to develop and refine in parallel three SB questionnaires: two age-specific instruments (adolescents, adults) and a common measure that may be suitable for both age-groups. We will determine the feasibility of the common measure using results from our descriptive studies, cognitive testing, and expert review. If it is feasible we will evaluate it in the second portion of our research. If not, we will evaluate the age-specific instruments. Second, we will conduct a reliability and validity study of the new SBQ(s) in a separate sample of adolescents (n=200) and adults (n=200) using both self-report and objective measures to establish criterion validity. In addition to evaluating the psychometric properties of the SBQs via factor analysis, we also will conduct exploratory analyses to identify a subset of items that could be used as a short-form of the instrument(s). Third, we will disseminate the new SBQs and their scoring algorithms for free via the web. We anticipate that the instruments developed in this research program will facilitate studies that attempt to describe where and why SBs occur, etiologic studies that examine the adverse effects of SBs on health, and clinical and intervention studies that seek to quantify changes in these behaviors in response to an intervention or health promotion program. PUBLIC HEALTH RELEVANCE: We are sedentary for the majority of our waking hours and time spent in these behaviors has been associated with obesity and chronic disease. The efforts of researchers and health care providers interested in sedentary behavior (SB) would be enhanced greatly by the existence of a valid and easy-to-administer instrument with which to measure SB. We seek to develop a questionnaire of manageable length that comprehensively assesses major SBs in the population. Inclusion of Women Plan: One-half of targeted and planned enrollment includes women. Inclusion of Minorities Plan: The targeted and planned enrollment includes representation of minorities that is consistent with the geographic location. Inclusion of Children Plan: The study will recruit an equal number of children (ages 12-17) as adults.
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会议论文
Modifiable Risk Factors for Fatal Prostate Cancer: A Prospective Study In Asia
  • 批准号:
    8451267
  • 项目类别:
  • 资助金额:
    $8.08万
  • 财政年份:
    2012
  • 负责人:
    Jay H. Fowke
  • 依托单位:
Modifiable Risk Factors for Fatal Prostate Cancer: A Prospective Study In Asia
  • 批准号:
    8302684
  • 项目类别:
  • 资助金额:
    $10.0万
  • 财政年份:
    2012
  • 负责人:
    Jay H. Fowke
  • 依托单位:
Biomarkers of Obesity, Prostate Tissue Inflammation, and BPH Progression
  • 批准号:
    8502655
  • 项目类别:
  • 资助金额:
    $32.94万
  • 财政年份:
    2010
  • 负责人:
    Jay H. Fowke
  • 依托单位:
Biomarkers of Obesity, Prostate Tissue Inflammation, and BPH Progression
  • 批准号:
    8098938
  • 项目类别:
  • 资助金额:
    $34.27万
  • 财政年份:
    2010
  • 负责人:
    Jay H. Fowke
  • 依托单位:
海外基金