CLINICAL TRIAL: INTRA-ORAL LIGHT ON GINGIVITIS (BLUE LIGHT STUDY)

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是评估将牙菌斑中的细菌暴露于可放置在口腔中的光源的效果。光用于治疗由细菌引起的其他疾病，如痤疮。 福赛斯的研究人员注意到，使用光系统美白牙齿的人，之后的牙龈炎（牙龈炎症）似乎较少。 他们还发现，当他们在实验室中对细菌照射类似类型的光时，一些细菌的数量会减少。受影响的细菌是导致牙龈疾病的细菌。 这项研究将观察一种特殊设计的光是否能减少牙菌斑和牙龈炎症中的细菌。 三十（30）名口腔两侧既存牙龈炎症的健康人群将参与本研究。 为了符合这项研究的条件，参与者必须在口腔两侧都有一定程度的牙龈炎症。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to evaluate the effect of exposing bacteria in dental plaque to a light source that can be placed in the mouth. Light is used to treat other conditions caused by bacteria, such as acne. Researchers at Forsyth have noticed that people who get their teeth whitened with a system that uses light seem to have less gingivitis (gum inflammation) afterward. They have also found that when they shine a similar type of light on bacteria in the laboratory, the numbers of some of the bacteria are reduced. The bacteria that are affected are the ones that are responsible for gum disease. This study will see if a specially designed light reduces the bacteria in plaque and gum inflammation. Thirty (30) generally healthy people with pre-existing gum inflammation on both sides of the mouth will participate in the study. To qualify for the study participants must have a certain amount of gum inflammation on both sides of their mouth.