ACTIVITY PACING AND SYMPTOMS IN OLDER ADULTS WITH OSTEOARTHRITIS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 骨性关节炎是导致老年人残疾的主要原因。下肢骨关节炎(LE-OA)与疼痛和疲劳症状有关，这些症状会影响活动能力。人们对患有LE-OA的老年人在日常生活中如何经历这些症状或他们做出的适应知之甚少，尽管这些适应被认为会影响残疾。该项目将研究适应与疼痛和疲劳症状之间的关系，将重点放在一个关键的适应上，即活动步调(例如，使用平衡活动与休息的策略)，并使用实时测量方法(例如，活动计分器)。将从密歇根大学S老年中心研究参与者计划招募60名年龄在55-80岁的女性：40名患有止痛性LE-OA的女性和20名健康对照。所有有兴趣前来筛查的受访者都将被告知这项研究，并被要求签署同意书。膝关节或髋关节骨性关节炎将首先通过放射检查确认。限制疼痛的髋关节或膝关节骨关节炎将通过在WOMAC疼痛分量表上获得5分或更高的分数来确定。参与者将回答有关人口统计学和身体机能的基本问题，并将参与步态、力量和平衡的身体表现评估。然后，参与者将接受佩戴活动评分设备的指导。设备将佩戴在手腕上五天，参与者将在一天中的六个时间点得到提示。在每个时间点，参与者将他们使用活动起搏的频率以及疼痛和疲劳程度输入到设备中。所有收集到的数据将汇编到计算机数据库中，在数据库中只能通过身份证号码识别参与者的身份。签署的知情同意书和将身份证号码与参与者姓名相匹配的主名单将保存在主要调查人员办公室的一个上了锁的抽屉里。该项目的具体目标是：1)检查五天内LE-OA相关症状的体验，将患有下肢OA的老年女性(LE-OA)的疼痛和疲劳水平的日变化(例如，每日)与健康女性对照组进行比较；2)在五天的测试期内，检查患有LE-OA的老年女性和对照组之间的活动起搏、疼痛和疲劳之间的关系。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Osteoarthritis is a leading cause of disability among older adults. Lower extremity osteoarthritis (LE-OA) is associated with symptoms of pain and fatigue that affect activity performance. Little is known about how older adults with LE-OA experience these symptoms in everyday life or the adaptations they make in response even though these adaptations are thought to influence disability. This project will investigate the relationship between adaptation and pain and fatigue symptoms by focusing on one key adaptation, activity pacing (e.g. use of strategies that balance activities with rest) and by using a real-time measurement method (e.g. acti-score devices). Sixty females aged 55-80 will be recruited from the Research Participant Program of the University of Michigan s Geriatric Center: 40 with pain-limiting LE-OA and 20 healthy controls. All interested respondents who come for screening will be informed about the study and asked to sign the consent form. Knee or hip osteoarthritis will be determined first through radiographic confirmation. Pain-limiting hip or knee osteoarthritis will be determined by having a score of five or greater on the WOMAC pain subscale. Participants will answer basic questions regarding demographics and physical function and will participate in physical performance assessments of gait, strength, and balance. Then participants will receive instruction on wearing the acti-score devices. Devices will be worn on the wrist for five days and participants will be prompted at six time-points throughout the day. At each time-point, participants will input their frequency of using activity pacing and pain and fatigue levels into the device. All data collected will be compiled into computer databases in which participants will only be identified from an ID number. Signed informed consent forms and a master list that matches ID numbers with participant names will be kept in a locked drawer in the principal investigators office. The specific aims of this project are 1) To examine the experience of LE-OA-related symptoms over a five-day period, the diurnal (e.g., daily) variations of pain and fatigue levels of older women with lower extremity OA (LE-OA) will be compared to healthy women controls and 2) To examine the relationship between activity pacing, pain, and fatigue among older women with LE-OA and the control group over a five day testing period.'