Biostatistics with a focus on cardiovascular health and minority populations

描述(由申请人提供)： 我们请求支持一项新的为期3年的NHLBI/NCRR本科培训助学金T-15，旨在鼓励高级本科生和初级研究生考虑在生物统计学领域就业。我们建议为对健康科学感兴趣的以定量为导向的本科生和初级研究生提供为期6周的协作生物统计学暑期住宿培训计划。该计划在心血管健康和少数群体多学科研究的背景下，突出了生物统计学的合作性质。具体目标是：(1)在引人注目的科学问题和真实数据的背景下，向受训者介绍基本的生物统计学方法；(2)向受训者传授自己解决这些问题所需的分析和计算机技能；(3)使受训者积极参与协作小组环境中的个别项目；以及(4)除了生物统计领域的进一步培训和就业机会外，对受训者进行关于生物统计思维在合作研究中的作用的教育。我们预计一年级培训20名学生，二年级和三年级各培训24名学生(三年共培训68名学员)。我们建议一个4学分的课程，包括一个综合的3学分的生物统计学入门课程和一个1学分的合作生物统计学研讨会。该课程由在基于人群的研究、临床试验、适应性设计、药物安全性、卫生服务研究、降低风险因素、少数民族健康、遗传学、人口学、调查抽样、地理编码和生物信息学领域的专业知识的合作生物统计学家授课。我们的合作者参与了几个由NHLBI资助的心血管疾病、肺炎和肺栓塞的大型试验，以及注册和基于人群的研究，作为临床导师参与。学生将在计算机实验室制作自己的案例研究笔记本。在研讨会上，学生们将以协作团队的形式进行互动，并根据NHLBI资助的研究、健康黑人家庭项目或阿勒格尼县卫生局的心血管数据集制作个人海报演示文稿。该方案将在每年年底使用重点小组进行评估，并根据咨询委员会的建议进行修订。该计划将突出统计思维在重要心血管项目中的作用，如果成功，将扩大可能考虑进一步培训生物统计学7相关性的学生群体：通过关注从我们自己的研究和直观的动手活动中提取的令人信服的生物医学例子，该计划可以通过以下方式吸引潜在学生进入生物统计领域：(1)具体例子证明生物统计学是生物医学研究的一个有趣组成部分；(2)临床合作者加强生物统计学贡献的价值；以及(3)学生认为自己正在做这类工作。(摘要结束)

DESCRIPTION (provided by applicant): We request support for a new 3-year NHLBI/NCRR undergraduate training grant T-15 designed to encourage advanced undergraduate and beginning graduate students to consider careers in biostatistics. We propose a 6-week residential summer training program in collaborative biostatistics for quantitatively- oriented undergraduate and beginning graduate students who are interested in the health sciences. This program highlights the collaborative nature of biostatistics within the context of multidisciplinary research studies in cardiovascular health and minority populations. The specific aims are to (1) introduce trainees to basic biostatistical methods in the context of compelling scientific questions and real data; (2) teach trainees the analytic and computer skills necessary to address these questions themselves; (3) actively involve trainees in individual projects within a collaborative group setting; and (4) educate trainees about the role of biostatistical thinking in collaborative research in addition to opportunities for further training and employment in the field of biostatistics. We anticipate training 20 students in Year 1 and 24 students each in years 2 and 3 (a total of 68 trainees in 3 years). We propose a 4-credit program comprised of an integrated 3-credit course in Introductory Biostatistics and a 1-credit Collaborative Biostatistics Seminar. This program is taught by collaborative biostatisticians with expertise in the areas of population-based studies, clinical trials, adaptive designs, medication safety, health services research, risk factor reduction, minority health, genetics, demography, survey sampling, geocoding, and bioinformatics. Our collaborators on several large NHLBI-funded trials in cardiovascular disease, pneumonia, and pulmonary embolism as well as registry and population-based studies participate as clinical mentors. Students will create their own case study notebooks in the computer laboratory. In the seminar, students will interact in collaborative teams and develop individual poster presentations based on cardiovascular datasets from NHLBI-funded studies, the Healthy Black Family project, or the Allegheny County Health Department. The program will be evaluated using focus groups at the end of each year, and revised according to suggestions of the Advisory Committee. This program will highlight the role of statistical thinking in important cardiovascular projects and, if successful, expand the population of students who might consider further training in biostatistics 7 RELEVANCE: By focusing on compelling biomedical examples drawn from our own research, and intuitive, hands-on activities, this program could attract prospective students to the field of biostatistics by (1) concrete examples demonstrating that biostatistics is an interesting component of biomedical research; (2) clinical collaborators reinforcing the value of biostatistical contributions; and (3) students seeing themselves doing such work. (End of Abstract)