Botanical Identification, Characterization, Quality Assurance/Ikhlas A. Khan

项目总结(见说明)： 为了对本植物学研究中心(BRC)所选的植物学标准物质有一个完整的了解，甘草-光果甘草变种光面甘草。野生山药-簇毛山药和冬瓜-当归(Oliv.)对于DIELS，人们不仅需要充分评估材料的形态组成，还需要检查必要的植物化学成分，并随后对每个选定物种的相关“生物标记”进行分析评估。要完成 这项任务，即植物鉴定、表征质量保证和质量控制核心(核心A)将满足以下特定目标。 具体目标1.通过以下途径鉴定上述物种的植物样本和提取物 利用适当的显微技术和/或植物化学评价(HPTLC、HPLC等)。 具体目标2.提供经鉴定的植物标本、大宗提取物、半纯化的裂解产物和所列植物及密切相关物种的纯化合物，以供其他项目内的生物学评估。分离的纯化合物将用于改进分析方法和相关的形态分析。 具体目标3.根据需要为必要的项目提供放大提取和隔离能力。 每个指定的目标将被量身定做，以适应相关研究项目1、2和3的特定研究要求。

PROJECT SUMMARY (See instructions): In order to have a complete understanding of the botanical reference material selected for study under this Botanical Research Center (BRC), Licorice - Glycyrrhiza glabra Linne var glabra. Wild Yam - Dioscorea villosa L., and Dong Quai - Angelica sinensis (Oliv.) Diels, one needs to fully evaluate not only the morphological makeup of the material but also examine the requisite phytochemical proflle and conduct the subsequent analytical assessment ofthe relevant "bio-markers" for each selected species. To accomplish this task, the Botanical Identiflcation, Characterization Quality Assurance and Quality Control Core (Core A) will meet the following speciflc aims. Speciflc Aim 1. Authenticate botanical samples and extracts ofthe aforementioned species through the utilization of appropriate microscopic techniques and/or phytochemical evaluation (HPTLC, HPLC, etc.). Specific Aim 2. Provide authenticated plant specimens, bulk extracts, semi-purified fracfions, and pure compounds of the listed plants and closely related species for biological assessment within the other projects. Isolated pure compounds will be utilized for refinement of analytical methodologies and related speciation analysis. Specific Aim 3. Provide scale up extracfion and isolation capabilifies as needed for the requisite projects. Each of the outiined aims will be tailored to suit the particular research requirements for the associated Research Projects 1, 2 and 3.