CO-FUNDED INSTRUMENTATION CORE

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 共同资助的仪器核心包括三个核心能力，位于特拉华州生物技术研究所，发挥关键和有利的作用，以促进生命科学为基础的研究在特拉华州大学和更广泛的研究社区在国家的一个多样化的群体。所涉及的设施包括： + 生物成像中心，一个多用户设施，涵盖了全面的电子，共聚焦，光和 扫描探针显微镜; + 蛋白质组学中心，提供测量和定量蛋白质表达谱的服务， 评估翻译后修饰; + 生物信息学中心，它提供了一系列的计算资源。 这些设施都不是由COBRE管理的;所有设施都是在收费服务的基础上运作的，并得到额外的机构和基础设施赠款支持。COBRE的支持请求为每个中心提供固定资金，允许所有COBRE研究人员的实验室扩展使用中心的服务。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Co-Funded Instrumentation Core comprises a diverse group of three core capabilities, located at the Delaware Biotechnology Institute, that play a critical and enabling role to facilitate life sciences-based research at the University of Delaware and in the broader research community in the state. The facilities involved are: + The Bioimaging Center, a multi-user facility covering a comprehensive array of electron, confocal, light and scanning probe microscopy; + The Proteomics Center, offering services for measuring and quantifying protein expression profiles and for assessing post-translational modifications; + The Bioinformatics Center, which provides a range of computing resources. None of these facilities is managed by the COBRE; all are operated on a fee-for-service basis with additional institutional and infrastructure grant support. The support request by the COBRE provides fixed funding to each of the centers, allowing all COBRE investigators' labs extended use of the services of the centers.