Colorado Career Development Program in the Genetics and Genomics of Lung Diseases

认识到遗传学和基因组学技术应用于人类疾病的重要性日益增长， 并意识到肺部疾病研究可以在多大程度上受益于这些药物的扩大使用 技术，我们提出了科罗拉多州肺遗传学和基因组学计划(CPGGP)，用于 肺部遗传学和基因组学研究学者的职业发展。 拟议职业发展计划的目标： 培养肺部疾病遗传学和基因组学临床研究领域的领导者 建立一个课程，结合我们现有的最好的肺部医学培训，人类医学 遗传学和临床科学课程 加强协作 招募来自不同背景的优秀学者 我们提议的计划响应NHLBI蓝图，并具有以下组件以实现 这些目标： 一门课程，旨在让所有学者对基础知识和 肺部疾病遗传学和基因组学研究的现实，无论其背景如何 通过正在进行的遗传学和/或基因组学研究之一的研究机会进行研究的广度 四种主要肺部疾病：急性肺损伤/急性呼吸窘迫综合征(ALI/ARDS)， 肺高压(PH)、慢性阻塞性肺疾病/癌症预防(COPD/CA)、 和肉芽肿性肺病 通过共同指导的研究项目进行协作 通过临床研究设计、监管方面的培训为独立的临床研究做准备 人类医学遗传学研究中固有的监督、拨款申请、人类受试者使用和伦理 计划评估和实习生跟踪 该计划吸收了肺部疾病、医学遗传学、生物信息学、 和临床科学培训计划，以便为学者提供重要选择的机会 关于他们通过该计划的旅程，并优化他们未来的成功。在当前的范例中， 不仅学者将受益，导师也将从他们参与该计划中受益。通过更多 该计划广泛涵盖选定的肺部疾病，可以对 遗传学和基因组学在肺部疾病中的应用。

In recognition of the growing importance of genetics and genomics techniques applied to human disease, and in awareness of the extent to which lung disease research could benefit from expanded use of these technologies, we propose the Colorado Pulmonary Genetics and Genomics Program (CPGGP) for the career development of scholars in pulmonary genetics and genomics research. Objectives of the proposed career development program: Train leaders in the field of clinical research in lung disease genetics and genomics Build a curriculum combining the best of our existing pulmonary medicine training, human medical genetics, and clinical sciences programs Increase collaboration Recruit excellent scholars from various backgrounds Our proposed program responds to the NHLBI blueprint and has the following components for achieving these objectives: A curriculum designed to bring all scholars to a commensurate understanding of the fundamentals and realities of lung disease genetics and genomics research, regardless of their background Breadth of study through research opportunities in ongoing genetics and/or genomics research in one of four major lung diseases: Acute Lung Injury / Acute Respiratory Distress Syndrome (ALI/ARDS), Pulmonary Hypertension (PH), Chronic Obstructive Pulmonary Disease / Cancer Prevention (COPD/CA), and Granulomatous Lung Disease Collaboration through co-mentored research projects Preparation for independent clinical research through training in clinical research design, regulatory oversight, grant writing, human subject use, and ethics inherent in human medical genetics research Program evaluation and trainee follow-up The Program assimilates the expertise resident in Pulmonary Diseases, Medical Genetics, Bioinformatics, and the Clinical Sciences Training Program in order to afford Scholars the opportunity for significant choices regarding their journey through the Program, and optimizing their future success. In the current paradigm, not only will Scholars benefit, but Mentors will also profit through their involvement in the Program. By more broadly covering selected Pulmonary Diseases, the Program can have a pronounced impact on the application of genetics and genomics to lung diseases.