Molecular targets involved in human muscle atrophy and hypertrophy

肌肉萎缩是衰老、癌症、艾滋病毒/艾滋病、肥胖和工伤的结果。它增加了受伤的风险，影响了康复，并给我们的医疗体系带来了经济负担。Atrogin-1和STAR是肌肉特有的基因，据信可以调节肌肉质量。该项目旨在确定人类阿托金-1和STARS是如何被调控的，以及它们如何影响肌肉损失。这些研究可能为减少人类肌肉损耗提供新的目标。

Muscle wasting is a consequence of aging, cancer, HIV-AIDS, obesity and work-sport injuries. It increases the risk of injury, impacts on recovery and places an economic burden on our healthcare system. Atrogin-1 and STARS are muscle specific genes believed to regulate muscle mass. This project aims to determine how human atrogin-1 and STARS are regulated and how they can influence muscle loss. These studies may provide new targets for reducing human muscle wasting.