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中文摘要
翻译
荷尔蒙和代谢物核心的使命是协助研究人员对啮齿动物模型中的各种血浆代谢物、激素、脂肪因子和细胞因子进行统一和标准化的分析,以及与肥胖和共病、能量平衡、饮食失调和营养相关问题的调节有关的人类研究。该中心提供的化验服务为了解肥胖及相关的糖脂代谢紊乱提供了一个综合的框架。此外,获得的数据与该中心的身体成分、动物能量平衡表型、脂肪细胞和分子遗传核心的分析直接相关并结合在一起。HMC提供的服务最好以核心实验室为基础,因为它们需要特殊的仪器和方法,这 在作为NYONRC成员的个别调查人员的实验室中建立这种技术是困难的,或者是不切实际的昂贵。
英文摘要
The mission of the Hormone & Metabolite Core is to assist investigators by performing uniform and standardized assays of various plasma metabolites, hormones, adipokines and cytokines in rodent models and human studies related to the regulation of obesity and co-morbidities, energy balance, eating disorders and nutrition related problems. The assay services provided within this Core provide an integrative framework for understanding obesity and associated disorders in glucose and lipid metabolism. In addition, the data obtained directly relate to and integrate with the analyses performed in the Body Composition, Animal Energy Balance Phenotyping, the Adipocyte and the Molecular Genetic Cores ofthe Center. The services provided at the HMC are best based in a Core Laboratory because they require special instrumentation and methodology, which would be difficult or impracticably expensive to establish in the laboratories of the individual investigators who are Members ofthe NYONRC.
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Administrative Core
Innovative translational medical nutrition training for non-physician scientists
Innovative translational medical nutrition training for non-physician scientists
Innovative translational medical nutrition training for non-physician scientists
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海外基金
支链氨基酸代谢紊乱调控“Adipocytes - Macrophages Crosstalk”诱发2型糖尿病脂肪组织功能和结构障碍的作用及机制