Mobile technology and online tools to track adherence in chronic illness patients

描述(由申请人提供)：目前美国每四个年轻人中就有一个患有慢性病，赋予年轻人拥有自己的医疗保健的权利是至关重要的。研究表明，从儿科护理成功过渡到以成人为重点的卫生保健系统的一个关键组成部分是适当地管理治疗方案[1]。不幸的是，青少年慢性病患者的治疗依从性低得令人失望，50%-70%的患者依从性差[2]。对依从性研究的回顾表明，随着疾病和治疗相关知识的增加，治疗不依从性的风险降低，提供行为管理组件可以优化依从性[8-10]。这一第二阶段SBIR项目的目标是继续研究和开发在线医疗监测系统(OMMS)，这是一个综合的在线和移动技术基础设施，专门设计用于：(A)通过互动和基于游戏的教育材料，加强青少年与疾病和治疗相关的知识；(B)通过移动和基于网络的交付，通过定制的任务提示，支持坚持治疗方案；以及(C)通过真实世界的数据收集和同步反馈循环，促进患者与提供者的沟通。在第二阶段，我们将在第一阶段反馈的基础上最终确定功能齐全的产品，并进行现场测试，检查OMMS在多大程度上提高了患有各种慢性病的青少年的治疗依从性。这一第二阶段项目将实现三个具体目标：1)全面开发OMMS产品；2)对患有慢性病的青少年OMMS的益处进行实地测试；3)最终完成OMMS并准备进行广泛的商业化。据我们所知，OMMS将是第一个将教育、依从性跟踪和患者与提供者沟通工具集成到一个全面、简化的包中的技术产品。我们期望OMMS能有效地为患有慢性病的青少年提供必要的信息和急需的支持，帮助他们成功地协商治疗方案，并过渡到自我管理的医疗保健。

DESCRIPTION (provided by applicant): With one out of every four youth in the United States currently living with a chronic illness, it is critically important to empower youth to take ownersip of their own healthcare. Research suggests that a key component of a successful transition from pediatric care into adult-focused health care systems is proper management of treatment regimens [1]. Unfortunately, treatment adherence among adolescents with chronic illness is disappointingly low, with poor adherence found in 50-70% of all patients [2]. Reviews of adherence studies indicate the risk of treatment nonadherence declines with greater disease- and treatment-related knowledge and that providing a behavioral management component optimizes adherence [8-10]. The goal of this Phase II SBIR project is to continue the research and development of the Online Medical Monitoring System (OMMS), an integrated online and mobile technology infrastructure specifically designed to (a) enhance youths' disease- and treatment-related knowledge through interactive and game-based educational materials; (b) support adherence to the treatment regimen through customized task prompts via mobile and web-based delivery; and (c) promote patient-provider communication through real-world data collection and synchronized feedback loops. During Phase II, we will build on Phase I feedback to finalize the fully functioning product and conduct a field test examining the degree to which the OMMS enhances treatment adherence outcomes among adolescents with a variety of chronic illnesses. This Phase II project will accomplish three specific aims: 1) fully develop the OMMS product; 2) conduct a field test of the benefits of the OMMS with adolescents with chronic illness; and 3) finalize the OMMS and ready for broad scale commercialization. To our knowledge, the OMMS will be the first technology product that integrates educational, adherence tracking, and patient-provider communication tools into one comprehensive, streamlined package. We expect the OMMS to effectively provide essential information and much needed support to youth with chronic illness to help them successfully negotiate their treatment regimen and transition into self-managed healthcare.