Methodology Core

RESCU（方法）核心： 核心单位人员将参与提供以下四项主要服务中的每一项：项目设计、统计支持、FRACITY/北京/MOST和OAI流行病学分析和管理。虽然为了便于介绍，可以单独考虑这些服务，但它们实际上代表了一个丰富的集成功能网络，将以多种方式促进MCRC的性能。首先，这些服务的集中有助于整合中心的多个研究项目，也有助于促进其管理。第二，核心服务职能将为流行病学和其他临床研究项目提供补充支持，这些项目是通过本MCRC提案资助的，并为其他来源资助或将由其他来源资助的一些其他项目提供补充支持。这个核心单位已经为多个外部资助的项目提供了大量的研究支持（例如三个中心赠款，四个R-01/U-01），并将在下一个5年周期继续这样做。RESCU还将为赠款周期内发展的新项目提供关键的启动支持。第三，核心将为其他研究活动提供服务，包括基础和临床研究项目，如血管炎和硬皮病。第四，核心资金将使我们的工作人员能够继续为其他关节炎单位的研究人员提供咨询支持。 核心单位安排将建立一个资源网络，将工作人员的职能扩展到其具体项目任务之外，并促进有效利用工作人员的时间。该中心资源的两个主要特点是该支持单位成员的共享办公空间，这使他们能够频繁互动，以及每周的工作人员会议（RESCU会议），其中正在进行的和拟议的研究项目进行批判性评估。继续这个成功的核心单位，因此将提供一套集中和共享的资源，这将提高我们的生产力在一个特殊的中心重点领域，并将有助于资源，以支持其他关节炎研究者谁需要设计和分析建议。

RESCU (Methodology) CORE: Core unit personnel will be involved in providing each of the following four major services: project design, statistical support, Framingham/Beijing/MOST and OAI epidemiologic analyses and administration. Although these services can be considered separately for ease of presentation, they in fact represent a rich network of integrated functions that will contribute to MCRC performance in a number of ways. First, the centralization of these services helps to integrate the multiple research projects of the Center and will also serve to facilitate their administration. Second, the core service functions will provide supplemental support for projects in epidemiology and other clinical research funded through this MCRC proposal and for a number of other projects that are or will be funded from other sources. This core unit already provides substantial research support for multiple externally funded projects (e.g. three center grants, four R-01/U-01's) and will continue to do so during the next 5 year cycle. RESCU will also provide critical start up support for new projects that evolve during the grant cycle. Third, the core will provide services to other research activities including basic and clinical research projects such as those in vasculitis and scleroderma. Fourth, core funds will enable our staff to continue their consultative support of researchers at other arthritis units. The core unit arrangement will create a network of resources that extends the functions of staff beyond their specific project assignments and facilitates the efficient use of staff time. Two key features of this central resources are the shared office space of members of this support unit which leads them to frequent interactions, and the weekly staff meetings (RESCU meetings) in which ongoing and proposed research projects are critically evaluated. The continuation of this successful core unit will thus provide a set of centralized and shared resources that will enhance our productivity in an area of special Center emphasis and that will contribute to a resource in support of other arthritis investigators who need design and analysis advice.