Summer Undergraduate Research Fellowship in the Molecular Biology and Genomics of Human Cancer

项目摘要/摘要 该计划的长期目标是建立一个夏季本科生研究奖学金。 杰克逊基因组医学实验室(JAX-GM)人类癌症的分子生物学和基因组学 在康涅狄格州法明顿，这将支持加强癌症研究和基因组学教育的必要性 未来的生物医学劳动力。这一拟议的计划将作为现有JAX中的一个已定义队列发挥作用 暑期学生计划(SSP)。杰克逊实验室是美国国家癌症研究所指定的癌症中心，JAX-GM 为具有不同癌症专业知识的科学家提供协作、高度创新的研究环境 将支持该计划的以下目标：(1)提供真实和有指导的研究体验。 JAX-GM将招募10名学生加入一个尖端的合作研究团队，使用分子和 研究人类乳房、卵巢、骨骼和脑的病因和进化的计算方法 癌症、白血病、癌症免疫治疗以及基因组结构变异和不稳定性。(二)推广 科学的多样性。参赛者将通过全国范围内的竞争性申请程序选出，以及 将通过有针对性的全国外联活动，积极招募任职人数偏低群体的成员。每位实习生 将获得全额奖学金，包括生活费、往返交通费、研究用品和 抵消了住房成本。这些资金将使经济困难的学生能够放弃暑期工作。 并参与这一改变人生的教育体验。(三)鼓励科学和终身发展 科学素养。每个参与者将加入一个赞助科学家的团队，并将设计和进行 独立的、假设驱动的项目，使用先进的分析方法和工具，以及杰出的科学 可在JAX-GM获得的资源。癌症研究奖学金计划将要求学生参加 关于当今科学家面临的伦理、法律和社会问题的研讨会和在线完成预科奖学金 癌症基因组学前传。(4)结合评估，加强项目建设。JAX基因组 教育人员将收集形成性和终结性评估数据，这些数据将直接为计划领导层提供信息 以指导未来对该计划的管理。JAX机构承诺确保学生能够访问 智力和研究资源，包括校园课程和会议、最先进的 仪器和计算资源，由JAX基因组教育人员专门负责项目指导， 以大学为背景的住房，以及专业人员的住宿计划。SSP--由 机构基金、私人基金会和联邦赠款--有完善的行政程序 招聘和选拔、导师培训、指导、项目设计、管理和评估。JAX-GM 提供一个激励的环境，在这个环境中，来自不同背景的有动力的有才华的学生可以学习 科学探究的基础，有助于真正的研究进步，并在智力和 个人成长将指导他们的职业选择和终身学习。

PROJECT SUMMARY / ABSTRACT The long-term goal of the proposed program is to establish a summer undergraduate research fellowship in the molecular biology and genomics of human cancer at The Jackson Laboratory for Genomic Medicine (JAX-GM) in Farmington, CT that will support the need for enhanced education in cancer research and genomics for the future biomedical workforce. This proposed program will function as a defined cohort within the existing JAX Summer Student Program (SSP). The Jackson Laboratory is a NCI-designated Cancer Center, and JAX-GM provides a collaborative, highly innovative research environment of scientists with diverse cancer expertise that will support the following aims of this program: (1) Provide an authentic and mentored research experience. JAX-GM will recruit ten students to join a cutting-edge, collaborative research team using molecular and computational methods to investigate the etiology and evolution of human breast, ovarian, bone, and brain cancers, leukemia, cancer immunotherapy, and genome structural variation and instability. (2) Promote diversity in science. The participants will be chosen through a competitive, nationwide application process, and members of underrepresented groups will be actively recruited through targeted national outreach. Each intern will receive a full fellowship including subsistence, round-trip transportation, research supplies, and funds to offset the cost of housing. These funds will enable economically disadvantaged students to forgo summer jobs and participate in this life-changing educational experience. (3) Encourage careers in science and lifelong scientific literacy. Each participant will join a sponsoring scientist's team and will design and conduct an independent, hypothesis-driven project using advanced analytic methods and tools and the outstanding scientific resources available at JAX-GM. The cancer research fellowship program will require students to attend workshops on the ethical, legal, and social issues facing scientists today and complete pre-fellowship online prequels on cancer genomics. (4) Incorporate evaluation to strengthen the program. JAX Genomic Education staff will collect formative and summative evaluation data that will directly inform program leadership to guide future administration of the program. The JAX institutional commitment ensures student access to intellectual and research resources including on-campus courses and conferences, state-of-the-art instrumentation and computational resources, dedicated program direction by JAX Genomic Education staff, housing in a college setting, and a professionally staffed residential program. The SSP––supported by institutional funds, private foundations, and federal grants––has well-established administrative procedures for recruitment and selection, mentor training, guidance, program design, management, and evaluation. JAX-GM offers a stimulating environment in which motivated, talented students from diverse backgrounds can learn the fundamentals of scientific inquiry, contribute to real research progress, and make great strides in intellectual and personal growth that will guide them in career choices and lifelong learning.