Chicagoland Diabetes TrialNet Clinical Center

描述(申请人提供)：本申请“芝加哥试验网临床中心”是对RFA-DK-13-0101型糖尿病试验网临床中心(U01)的响应。在这里，我们描述了芝加哥大学和Advocate儿童医院(ACH)网站(Park Ridge和Oak Lawn，伊利诺伊州)和Advocate Health Care(AHC)在芝加哥地区创建一个新的临床中心的联合努力。这些组织以及我们的其他附属机构(Lurie儿童医院)和合作伙伴网站在2012年接待了9000多名1型糖尿病(T1D)患者。这些实习地点与来自芝加哥的其他参与的关键成人和儿科糖尿病实践者一起，在距离筛查地点两个小时的车程内接触到超过1200万人。芝加哥社区是青少年糖尿病研究基金会(JDRF)和美国糖尿病协会(ADA)的坚定支持者，在1型糖尿病(T1D)的临床试验中一直代表不足。这一伙伴关系将汇集致力于T1D研究和临床护理的主要医疗中心的资源，以帮助芝加哥地区约10万T1D患者(约占该地区人口的0.8%)及其家人中的更多人，以及每年预计的2000例T1D新病例及其家人。这种外展将涉及不同的社区，从美国最富有的一些人到服务最少的一些人。我们将在成功创建美国最大的单基因糖尿病数据库基础上再接再厉。我们将通过创新的社交媒体和直接沟通，结合媒体支持、对当地实践的直接访问、由我们的机构和合作伙伴支持的社区活动以及与大型信仰社区网络的外联，与大芝加哥社区打交道。100多年来，芝加哥大学一直致力于糖尿病研究，我们将与Advocate儿童医院和其他合作伙伴一起，为芝加哥地区TrialNet的招募和筛选带来新的活力、组织和目标。

DESCRIPTION (provided by applicant): This application "Chicagoland TrialNet Clinical Center" is in response to the RFA -DK-13-010 Type 1 Diabetes TrialNet Clinical Centers (U01). Here we describe a joint effort from the University of Chicago and Advocate Children's Hospital (ACH) sites (Park Ridge and Oak Lawn, Illinois) and Advocate Health Care (AHC) to create a new Clinical Center in the Chicagoland area. These organizations along with our other affiliate (Lurie Children's Hospital) and partner sites saw over 9000 patients with type 1 diabetes (T1D) in 2012. Together, these practice sites along with other participating key adult and pediatric diabetes practitioners from Chicago reach over 12 million individuals within a two-hour drive of a screening location. The Chicago community, strong supporters of the Juvenile Diabetes Research Foundation (JDRF) and American Diabetes Association (ADA), has been under-represented in clinical trials for Type 1 Diabetes (T1D). This partnership will bring together the resources of major medical centers committed to T1D research and clinical care to reach more of the estimated 100,000 individuals with T1D in the Chicagoland area (about 0.8% of the area population) and their families, as well as the 2000 projected new cases of T1D and their families each year. This outreach will involve diverse communities from some of the wealthiest to some of the most underserved in the United States. We will build on our success in creating the largest database for monogenic diabetes in the United States. We will engage the greater Chicagoland community through innovative social media and direct communications combining media support, direct visits to local practices, community events supported by our institutions and partners and outreach to large networks of faith communities. The University of Chicago has been committed to diabetes research for over 100 years, and together with Advocate Children's Hospital and other partners we will bring a new sense of energy, organization, and purpose to TrialNet recruitment and screening in the Chicagoland region.