NExT NX232-107-158-006 TO#3 Milestone 3 (base) - PK & Bioavail Stud w/Selected Anticancer Compounds in Mice, PK & Pharm Evals of Agents Being Developed for Cancer Patients, HHSN261201600024I/HHSN26100

本课题的目的是研究小分子候选抗癌化合物在小鼠体内的血浆药代动力学(PK)和生物利用度，以支持NEXT项目团队(S)。需要迅速扭转研究结果。根据该任务顺序，有九(9)个选项可供选择进行额外的学习。需要提交一份全面的电子表格(Excel)，其中包含所有研究的化合物的数据。这将使下一个项目团队能够对化合物进行全面分析。

The purpose of this Task Order is to characterize the plasma pharmacokinetics (PK) and bioavailability of small molecule candidate anticancer compounds in mice in support of NExT project team(s). Rapid turn-around of study results is required. There are nine (9) options for additional studies under this task order. Delivery of a comprehensive spreadsheet (Excel) containing data for all compounds studied is required. This will allow the NExT project team to conduct a comprehensive analysis across compounds.